“…Most of the cases that integrate these two approaches belongs to the kind of problems with solutions that present strongly undetermined polynomial time (strongly NP-hard), so they are a challenge for achieving an optimal solution (IORI; MARTELLO, 2016). This is the case of the VRP, which is well-known as an NP-hard problem (PIQUERAS, 2002;LÜER et al, 2009;MEDINA et al 2011;CHOWMALI;SUKTO, 2020), and it is a famous problem in operations research and combinatorial optimization (CHOKANAT et al, 2019;WICHAPA; KHOKHAJAIKIAT, 2018). The vehicles freight distribution problem with loading constraints is also considered as NP-hard problem (PACE et al, 2015).…”