A novel strategy to determine As, Cr, Hg and V in drinking water by ICP-MS/MS

Abstract

This work demonstrates the potential of inductively coupled plasma tandem mass spectrometry (ICP-MS/MS) in trace element analysis. Aiming Hg determination in water, sample preservation requires chloride addition, which presents formation of polyatomic interfering ions as a drawback for the determination of other analytes (e.g. As and V). Thus, the effect of chloride on As, Cr, V and Hg determination and the feasibility of using ICP-MS/MS to circumvent the interference were evaluated. A standard reference material (NIST SRM 1643e) and recoveries from tap water spiked with As, Cr, Hg and V were used for accuracy assessment and for the evaluation of matrix effects. The reaction between Hg and oxygen gas is not favorable in the octopole reaction system (ORS 3 ). Therefore, Hg was accurately determined as a single atom ion ( 202 Hg + ) under the same analytical conditions adopted for As, Cr and V determination by monitoring 75 As 16 O + , 52 Cr 16 O + and 51 V 16 O + while the ORS 3 was pressurized with oxygen gas. The oxygen reaction mode significantly improved the accuracy for As, Cr and V, especially at the lowest spiked level, which is strongly affected by matrix effects. The signal gain in m/z 75 for a solution containing 1 mg L À1 As in 0.48 mol L À1 chloride medium was 1974% when employing single quadrupole mode. On the other hand, the signal increased only 7% when 0.75 mL min À1 O 2 was used in mass shift mode proving the efficiency of the MS/MS mode. Thus, ICP-MS/MS and ORS 3 pressurized with O 2 gas effectively reduced the interference, and enhanced the accuracy and sensitivity for some specific isotopes in a complex medium. The limits of detection for V ( 51 V 16 O + ), Cr ( 52 Cr 16 O + ), As ( 75 As 16 O + ) and Hg ( 202 Hg + ) were estimated to be 2, 3, 1.6 and 38 ng L À1 at the 99.7% confidence level, respectively.

Determination of Ca, Cd, Cu, Fe, K, Mg, Mn, Mo, Na, Se, and Zn in Foodstuffs by Atomic Spectrometry After Sample Preparation Using a Low-Cost Closed-Vessel Conductively Heated Digestion System

“…It presents an octopole reaction system (ORS 3 ) located in-between two quadrupole analyzers and allows the operation of the ICP-MS instrument in MS/MS mode. This configuration improves the control of collision and reaction processes inside the ORS 3 due to the pre-selected mass/charge ratio, and it has been successfully applied in order to determine several elements in different types of sample (Balcaen et al 2013;Amais et al 2014Amais et al , 2015Amaral et al 2015;Virgilio et al 2015).…”

ICP-MS/MS as a tool to study abiotic methylation of inorganic mercury reacting with VOCs

“…The productivities of the gaseous CH 3 Hg + ions by CH 3 I in the dark reactor in our work are close to the productivities of the aqueous CH 3 Hg + ions by UV irradiation reported by Yin et al 16 In addition, our work also demonstrates that this methylation reaction can occur even at extremely low gas pressures, for the ORS 3 in the ICP-MS/MS is a near-vacuum environment. 27,[30][31][32][33] In this study, we use an ICP-MS/MS instrument as the tool to study inorganic mercury methylation, which expands the application range of ICP-MS/MS for elements determination. Fig.…”

Lewisite exposure biomarkers in urine by liquid chromatography – inductively coupled plasma tandem mass spectrometry: with an accelerated matrix-matched stability study

“…S1 †). 31 Four L1 metabolites can be resolved using different column dimensions without the oxidation step during sample preparation (Fig. Weapons-grade Lewisite contained on average $1% wt gem-L1; however, in some munitions the geminal isomer was not detectable.…”