A Novel Rhein-Functionalized Resin with Application for the Preconcentration of Anthraquinones

Xie, Jing; Liao, Xun; Qing, Fangzhu; Luo, Pei; Zhang, Zhifeng; Huang, Jing; Qing, Lin-Sen

doi:10.1080/00032719.2014.908383

Cited by 4 publications

(4 citation statements)

References 33 publications

(26 reference statements)

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“…Chrysophanol (also known as 1,8‐dihydroxy‐3‐methyl‐anthraquinone and chrysophanic acid, CAS No. : 481‐74‐3) (Figure ) is a naturally occurring anthraquinone that was found in traditional Chinese medicines, including Radix et Rhizoma Rhei , Cassia obtusifolia L., Polygonum multiflorum , Aloe vera var. chinensis (Haw.)…”

Section: Introductionmentioning

confidence: 99%

Chrysophanol: a review of its pharmacology, toxicity and pharmacokinetics

Xie

Tang

Song

et al. 2019

Journal of Pharmacy and Pharmacology

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Objective Chrysophanol is a natural anthraquinone, also known as chrysophanic acid and 1,8‐dihydroxy‐3‐methyl‐anthraquinone. It has been widely used in the food and pharmaceutical fields. This review is intended to provide a comprehensive overview of the pharmacology, toxicity and pharmacokinetic researches of chrysophanol. Key finding Information on chrysophanol was collected from the Internet database PubMed, Elsevier, ResearchGate, Web of Science, Wiley Online Library and Europe PM using a combination of keywords including ‘pharmacology’, ‘toxicology’ and ‘pharmacokinetics’. The literature we collected included from January 2010 to June 2019. Chrysophanol has a wide spectrum of pharmacological effects, including anticancer, antioxidation, neuroprotection, antibacterial and antiviral, and regulating blood lipids. However, chrysophanol has obvious hepatotoxicity and nephrotoxicity, and pharmacokinetics indicate that the use of chrysophanol in combination with other drugs can reduce toxicity and enhance efficacy. Summary Chrysophanol can be used in many diseases. Future research directions include how the concentration of chrysophanol affects pharmacological effects and toxicity; the mechanism of synergy between chrysophanol and other drugs.

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Section: Introductionmentioning

confidence: 99%

Chrysophanol: a review of its pharmacology, toxicity and pharmacokinetics

Xie

Tang

Song

et al. 2019

Journal of Pharmacy and Pharmacology

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“…The only example in the field of selective adsorption of anthraquinones has been reported in 2014 by Xie and coworkers. 34 These authors synthesized a rhein-functionalized resin by 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide-promoted condensation of compound ( 5) with an aminomethylpolystyrenebased resin. The linkage consisted in an amide bond between the -COOH group of rhein and the amino groups of the polystyrene skeleton.…”

Section: Functionalized Resinsmentioning

confidence: 99%

“…While this has been widely exploited for the removal of a plethora of polluting substances from wastewaters and the environment in general, it has found very little application in phytochemistry. The only example in the field of selective adsorption of anthraquinones has been reported in 2014 by Xie and coworkers 34 . These authors synthesized a rhein‐functionalized resin by 1‐(3‐dimethylaminopropyl)‐3‐ethylcarbodiimide‐promoted condensation of compound ( 5 ) with an aminomethylpolystyrene‐based resin.…”

Section: Functionalized Resinsmentioning

confidence: 99%

Solid‐phase adsorption methodologies of naturally occurring anthraquinones: A review

Palumbo

Fiorito

Epifano

et al. 2023

Phytochemical Analysis

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Introduction: Solid-phase extraction applied to plant matrices is nowadays a wellvalidated technique allowing to concentrate and purify different secondary metabolites. Several classes of phytochemicals have been selectively extracted by this methodology. During the last decade attention has been focused on biologically active anthraquinones from numerous sources like edible, healthy, and medicinal plants. Objectives: The aim of this review is to provide a detailed literature survey of the solid-phase adsorption methodologies for the extraction of natural anthraquinones reported so far and to discuss and propose future directions in this field of research. Materials and Methods: Substructure search was performed in the SciFinder Scholar, PubMed, Medline, and Scopus databases. Results: The first report about application of solid-phase adsorption for the purification of anthraquinones appeared in the literature in 2002. From this date, and in particular during recent years, the most notable examples included the use of chitin-and chitosan-based polymers, of molecularly imprinted polymers, of coated magnetic nanoparticles, of miniaturized matrix solid-phase dispersion, of functionalized resins, of differently structured lamellar solids, and finally of vortex-synchronized matrix solid-phase dispersion. Conclusions:The herein detailed solid-phase adsorption methodologies are powerful tools to selectively extract natural anthraquinones and/or provide anthraquinoneenriched phytopreparations. Nevertheless, many other important methods have been applied to synthetic anthraquinones (e.g., azo dyes). These could be conveniently employed also for natural anthranoids. Studies in this field are discussed in this review article.

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“…Nowadays, the design and preparation of fluorescent sensors is a research topic of great interest because of the high demand that these devices have in fields such as analytical chemistry, clinical biochemistry and medical research. One strategy to development of this kind of devices consists in the covalently attachment of fluorescent chemosensors (molecules whose fluorescence emission changes in response to a binding event) to the surface of solid supports (Akhila Maheswari and Subramanian, 2003;Kara, 2005;Narin et al, 2003;Prabhakaran and Subramanian, 2003;Xie et al, 2014).…”

Section: Introductionmentioning

confidence: 99%