A novel research on serpentine microchannels of passive micromixers

Chen, Xueye; Li, Tiechuan; Hu, Zengliang

doi:10.1007/s00542-016-3060-7

Cited by 54 publications

(22 citation statements)

References 15 publications

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“…The effective control of partially mixed samples is critical in the design of a concentration gradient generator. In recent years, we have carried out a series of studies on design [14], simulation [15,16], optimization [17,18], and fabrication [19] of micromixers.…”

Section: Introductionmentioning

confidence: 99%

Design and Fabrication of Concentration‐Gradient Generators with Two and Three Inlets in Microfluidic Chips

Chen

Wang

2017

Chem Eng & Technol

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A simple and low-cost method for designing and fabricating concentrationgradient generators with two and three inlets is proposed which can generate different concentration gradients at varying flow velocities. The microchannel structure was designed in S-shape and left-right symmetry. The concentration-gradient generator was simulated based on the finite element method. The microchannels were processed on a computer numerical control (CNC) engraving and milling machine on poly(methylmethacrylate) substrate, and then two concentrationgradient generators were fabricated by hot bonding technology. The results of experiment and simulation were compared to prove the feasibility of the method. Flow velocity was an important factor for generating different concentration gradients. The concentration-gradient profiles of the generators with two and three inlets present approximately linear and quadratic curves.

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Section: Introductionmentioning

confidence: 99%

Design and Fabrication of Concentration‐Gradient Generators with Two and Three Inlets in Microfluidic Chips

Chen

Wang

2017

Chem Eng & Technol

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“…Nanofluid particles smaller in size hold more particles than larger ones. Nanofluids with smaller particles can influence higher particle movement, improved interaction with base fluid, and increased transport energy, resulting in an increase in the Nusselt number 45 . Due to the increased contact time between the fluids and the base sink, more heat energy is observed through the channel at a lower nanofluid rate.…”

Section: Resultsmentioning

confidence: 99%

Thermal performance of U‐shaped serpentine microchannel heat sink using various metal oxide nanofluids

Sivakumar¹,

Sathiyamoorthi²,

Alagumurthi

et al. 2020

Heat Trans

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This study aims to evaluate the thermal performance and friction factor characteristics of the U‐shaped serpentine microchannel heat sink using three different nanofluids. Two distinct nanoparticles, namely Al2O3 (alumina) and CuO (copper oxide), were used for the preparation of nanofluids using water and ethylene glycol (EG) as base fluids. Three nanofluids, namely nanofluid I (Al2O3 + water), nanofluid II (CuO + water), and nanofluid III (CuO + EG), have been prepared. The results showed that the thermal conductivity of nanofluids was increased for all concentrations (from 0.01 to 0.3%), compared with base fluids. The theoretical values derived from the relationship between the Darcy friction factor showed a clear understanding of the fully developed laminar flow. Thermal resistance for nanofluid III was lower than other nanofluids, resulting in a higher cooling efficiency. The nanofluid mechanism and the geometry of the U‐shaped serpentine heat sink have led to the improvement in the thermal performance of electronic cooling systems.

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“…Fluid flow in microfluidic channels is known for its laminar behaviour, where streamlines do not cross paths. Special channel configurations, however, induce passive mixing [31][32][33][34][35][36][37][38][39][40][41][42].…”

Section: Effect Of Curvesmentioning

confidence: 99%

Study of the geometry of open channels in a layer-bed-type microfluidic immobilized enzyme reactor

2021

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This paper aims at studying open channel geometries in a layer-bed-type immobilized enzyme reactor with computer-aided simulations. The main properties of these reactors are their simple channel pattern, simple immobilization procedure, regenerability, and disposability; all these features make these devices one of the simplest yet efficient enzymatic microreactors. The high surface-to-volume ratio of the reactor was achieved using narrow (25–75 μm wide) channels. The simulation demonstrated that curves support the mixing of solutions in the channel even in strong laminar flow conditions; thus, it is worth including several curves in the channel system. In the three different designs of microreactor proposed, the lengths of the channels were identical, but in two reactors, the liquid flow was split to 8 or 32 parallel streams at the inlet of the reactor. Despite their overall higher volumetric flow rate, the split-flow structures are advantageous due to the increased contact time. Saliva samples were used to test the efficiencies of the digestions in the microreactors. Graphical abstract

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A novel research on serpentine microchannels of passive micromixers

Cited by 54 publications

References 15 publications

Design and Fabrication of Concentration‐Gradient Generators with Two and Three Inlets in Microfluidic Chips

Design and Fabrication of Concentration‐Gradient Generators with Two and Three Inlets in Microfluidic Chips

Thermal performance of U‐shaped serpentine microchannel heat sink using various metal oxide nanofluids

Study of the geometry of open channels in a layer-bed-type microfluidic immobilized enzyme reactor

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