A novel quinolinyl-tetraphenylethene-based fluorescence “turn-on” sensor for Zn²⁺ with a large Stokes shift and its applications for portable test strips and biological imaging

Abstract

A new 8-hydroxyquinoline derivative bearing the hydroxytetraphenylethene moiety called TPE(OH)-8HQ has been designed, synthesized and evaluated as an efficient fluorescence “turn-on” sensor for detection of Zn2+ based on chelation-enhanced fluorescence...

A fluorescent nanoprobe based on AIEgen: Visualization of silver ions and sensing applications in cancer cells and S. aureus

“…3a) and a weak emission peak at 474 nm (Fig. 3b) with a large Stokes shift in DI H2O (153 nm) and PBS (140 nm) (Table S2) [40]. AgP-1 showed no fluorescence in low-viscosity organic solvents such as ethanol (EtOH), ethyl acetate (EA), acetonitrile (ACN), tetrahydrofuran (THF), dimethyl sulfoxide (DMSO) with slight Stokes shift (Fig.…”

ESIPT-Active 8-Hydroxyquinoline-Based Fluorescence Sensor for Zn(II) Detection and Aggregation-Induced Emission of the Zn(II) Complex

“…The chelation of metal cations could remove the proton of −OH or −NH 2 , then the ESIPT process would be prohibited with significant spectral changes. 1 − 3 Therefore, one of the most important applications of ESIPT is the fluorescence sensors for metal ions. Fluorescence sensors based on ESIPT usually exhibit abnormally large Stokes shifts to avoid self-absorption.…”

“…Therefore, 8-hydroxyquinoline derivatives have been employed to develop novel fluorescence sensors to visualize metal cations via ESIPT suppression. 3 , 9 , 10 …”

Selective and Sensitive Discrimination of Zinc and Cadmium Based on a Novel Fluorescent Porous Organic Polymer

“…Fluorescence methods with high sensitivity, rapidity and costsaving have become one of the best solutions to the above problems [12][13][14][15][16][17]. Until now, various fluorescence probe have been reported for Zn 2+ and Cd 2+ detection, such as naphthalimide-derived fluorophore [18], DNAzyme [19], quinoline derivatives [20,21], diarylethene derivatives [22], cephem-based probe [23] and dansyl-appended tetrapeptide [1]. The reported fluorescence methods normally detect Zn 2+ or Cd 2+ based on fluorescence changes induced by the coordination of Zn 2+ or Cd 2+ with probes, however, the selectivity towards Zn 2+ or Cd 2+ are insufficient since the two metal ions have similar electron configuration and coordination features and both of them can simultaneously coordinated with fluorescence probes [24].…”

“…Up to now, Zn 2+ and Cd 2+ discrimination is still challenging but promising, and delicate fluorescent probes have been developed for selective detection of Zn 2+ and Cd 2+ . For example, Chen's group constructed a benzothiazole-based fluorescent probe using cysteine as an auxiliary reagent while Zhang et al developed a quinoline-based ratiometric fluorescent probe with different binding modes and Hou's group designed and synthesized a naphthalimidederived fluorescent probe based on amide tautomerization for efficient detection and distinguishing of Cd 2+ from Zn 2+ [16,18,21].…”