A novel porcine collagen GTR membrane for treatment of Class II molar furcation involvement

Abstract

Guided tissue regeneration (GTR) in the management of the periodontal furcation invasion is effective. Recent studies showed significant clinical improvement with different materials. The purpose of this study is to provide clinical evaluations of the bone repair potential of GTR combined with a novel porcine collagen membrane in the treatment of human molar Class II furcations. Fifty-one patients, 33 males and 18 females, with no systemic disease and a mean age of 49.1 years, participated in this study after phase I periodontal therapy. Probing depth, attachment loss and radiographic examination were recorded and analyzed before and after GTR therapy with collagen membrane. In the soft tissue measurement, the periodontal pocket (PD) depth was 5.283 ± 0.283 mm before the surgery and improved to 2.631 ± 0.147 mm at 9 months after surgery (p < 0.05). Attachment loss also showed similar results. The attachment level was 5.547 ± 0.3 mm before the surgery, and 2.911 ± 0.188 mm at 9 months after surgery (p < 0.05). According to the measurements the attachment gain was 2.636 ± 0.168 mm after GTR surgery with porcine collagen membrane. According to this study, the porcine collagen membrane can perform with exceptional results in attachment level gain for the Class II periodontal furcation involvement.

Guided Tissue Regeneration Treatment Yields Better Results in Class II Furcations in the Mandible Than in the Maxilla: A Retrospective Study

“…The Ethics Committee and Joint Institutional Review Board of Taiwan approved the study protocol of Taipei Medical University No. 201105001, (this approval was also previously used to publish the pilot results of the present study [ 13 ]). A total of 60 class II furcation defects in the upper and lower molars of 60 systematically healthy patients with periodontitis were included in the study after receiving phase I periodontal therapy, which comprised oral hygiene instructions, scaling, and root planning.…”

“…The surgical procedures were previously reported. Briefly, the surgery included sulcular incisions, full-thickness flap elevation, soft tissue debridement, and root planning ( Figure 2 ) [ 13 ]. Cervical enamel projections were eliminated using rotary dental instruments.…”

“…It was found that both treatments had comparable clinical effectiveness [ 11 ]. A novel porcine collagen membrane used in vivo and in human molars gained considerable attachment, making it a suitable option for improving new bone regeneration in furcation involvement [ 12 , 13 ]. The combined GTR treatment enhanced the vertical probing depth (PD), attachment level gain, and horizontal bone level (BL) gain compared with the resorbable membrane alone [ 14 ].…”