A novel phospho triazine compound serving as an anticancer and antibacterial agent: An experimental-computational investigation

Structural, Hirshfeld surface and molecular docking studies of a new organotin(IV)-phosphoric triamide complex and an amidophosphoric acid ester proposed as possible SARS-CoV-2 and Monkeypox inhibitors

“…A number of phosphoramide compounds and their organotin(IV) complexes have been structurally studied [ [6] , [7] , [8] ], where some of them have significant medicine applications such as antiviral, antitumor and anticancer activities [ [9] , [10] , [11] , [12] ]. Antibacterial and antimicrobial properties also have been found for some of phosphoramidate derivatives [ [13] , [14] , [15] , [16] ]. Moreover, some of these compounds are found to be the significant promising candidates to inhibit coronavirus [ [17] , [18] , [19] ]: some of the current not-optimal anti-coronavirus drugs, Remdesivir and Sofosbuvir, belong to the phosphoramides family [ 20 , 21 ].…”

N,2,6-Trisubstituted 1H-benzimidazole derivatives as a new scaffold of antimicrobial and anticancer agents: design, synthesis, in vitro evaluation, and in silico studies

“…The dual-acting anticancer and antimicrobial chemotherapy agents have been published in many studies. 4,[43][44][45][46] Moreover, people with cancer may have a higher risk of infection due to changes in the immune system that controls their body's defenses. 47 Therefore, our potential derivatives have shown to be promising agents in the development of dual therapeutic effects.…”