A novel nanozyme based on selenopeptide-modified gold nanoparticles with a tunable glutathione peroxidase activity

Abstract

A tunable glutathione peroxidase nanozyme based on the active center of enzyme functionalized gold nanoparticles.

Glutathione peroxidase-like nanozymes: mechanism, classification, and bioapplication

“…Of all the studies conducted on GPx-like nanozymes, one involved GPx-like nanozymes that followed an ordered mechanism. 59 By modifying Au NPs with selenium-containing pentapeptides, GPx-like nanozymes were constructed (Fig. 3B).…”

A colorimetric sensing platform for the determination of H2O2 using 2D–1D MoS2-CNT nanozymes

“…Each experiment was repeated three times. The kinetics constants were determined by double reciprocal plots and eqn (1), where K m is the Michaelis constant, V 0 is the initial reaction rate, V max is the maximum reaction rate, and [S] is the substrate concentration.…”

“…Nanozymes are new articial enzymes, which have the characteristics of both nanomaterials and natural enzymes. 1,2 However, compared with traditional natural enzymes, nanozymes have a series of unique advantages such as high stability, low cost and easy preservation. 3,4 Therefore, increasing research is devoted to related elds, including biomedical diagnostics, 5,6 food safety, 7 environmental monitoring 8 and antibacterial agents.…”

Synthesis, Catalytic Properties and Application in Biosensorics of Nanozymes and Electronanocatalysts: A Review

“…Development of new nanocatalysts, including NZs, with higher catalytic activity expands their applications in bioanalytics. As a rule, the activity of NZs is lower than that of enzymes and their catalytic performance strongly depends on: (1) the method of synthesis (pH, reaction time and temperature) [25]; the composition of the nanomaterial [16,65]; the shape, size, dispersity and final morphology [66]; the mass ratio of the components in the nanocomposite [67]; and surface functionalization [40,[68][69][70].…”

“…Three-dimensional nanomaterials, containing confined single atoms, possess increased catalytic activity due to mutual effects of unique geometric and electronic structures of the matrix and intrinsic catalytic activity of confined atoms [65]. Shackery and coworkers [72] recently prepared a glucose oxidase-like catalyst based on cobalt hydroxide [Co(OH) 2 ] nanorods on a 3D-graphene network using the chemical deposition method.…”