A novel nanomolar highly selective fluorescent probe for imaging mercury (II) in living cells and zebrafish

A Novel Camphor-Based “Turn-on” Fluorescent Probe with High Specificity and Sensitivity for Sensing Mercury(II) in Aqueous Medium and Its Bioimaging Application

“…Moreover, in order to further estimate the sensitivity of CP-Hg for determining trace Hg 2+ , a more accurate linear equation ( R 2 = 0.9946) between fluorescence intensity at 518 nm and the lower concentration of Hg 2+ (0–4 μM) was plotted as F 518 nm = 5.9829 × [Hg 2+ ] + 4.4884 (Figure S4); in this case, the detection limit of CP-Hg toward Hg 2+ was determined to be 1.93 × 10 –8 M, according to the formula 3σ bi / m , which was lower than the maximum allowable levels formulated by WHO and those of other reported Hg 2+ -specific probes (Table ). − Additionally, the probe CP-Hg also showed some prominent advantages such as wide linear range, superior detection medium, and multiple practical applications. All these data indicated that the probe CP-Hg has superior sensitivity for Hg 2+ .…”

A Pyrazolo Imine‐based Colorimetric and Turn‐on Fluorescent Sensor Probe for Determination of Hg2+ Ion and its Application in Test Paper Strips

“…The pyrene-based derivatives show good selectivity and sensitivity toward Hg 2+ ion as well as micromolar limit of detection, which has been reported by Wei Huang et al (7). Turn-on fluorescence sensor of pyrene-based chemosensors for the detection of Hg 2+ ions and its application in living cells and zebrafish has been reported by Shu-Pao Wu et al (25). Turn-off fluorescence sensing based 2-amino pyridine derivative for the selective detection of Hg 2+ and Fe 3+ were reported by Subrata Ghosh et al (26).…”

“…Turn‐on fluorescence sensor of pyrene‐based chemosensors for the detection of Hg 2+ ions and its application in living cells and zebrafish has been reported by Shu‐Pao Wu et al . (25). Turn‐off fluorescence sensing based 2‐amino pyridine derivative for the selective detection of Hg 2+ and Fe 3+ were reported by Subrata Ghosh et al .…”

A coumarin‐based fluorescent probe for Hg2+ and its application in living cells and zebrafish

“…[10][11][12][13] In recent years, some Hg fluorescent probes have been developed based on coumarin, BODIPY, rhodamine, and other dyes and applied for environmental and biological detection. [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31] However, most existing Hg 2+ fluorescent probes still have many shortcomings. For example, some fluorescent probes are not sufficiently sensitive, which severely limits their practical application for Hg detection.…”

“…For example, some fluorescent probes are not sufficiently sensitive, which severely limits their practical application for Hg detection. [23,[32][33][34][35] Other probes are poorly water soluble and cannot be used in cells and organisms. [36,37] Therefore, the development of a sensitive and selective Hg 2+ fluorescent probe that can be applied to environmental and biological samples is still a serious challenge.…”