A novel model of cutaneous candidiasis produced in prednisolone-treated guinea-pigs

Maebashi, Kazunori; Itoyama, Toshio; Uchida, Katsuhisa; Suegara, Nobuo; Yamaguchi, H.

doi:10.1080/02681219480000471

Cited by 31 publications

(22 citation statements)

References 18 publications

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“…albicans. C. albicans strain TIMM2640 (Teikyo University Institute of Medical Mycology, Tokyo, Japan), a clinical isolate from a patient with cutaneous candidiasis (Maebashi et al, 1994), was stored at À80 8C in Sabouraud dextrose broth (Becton Dickinson) containing 0 . 5 % (w/ v) yeast extract (Becton Dickinson) and 10 % (v/v) glycerol until used for experiments.…”

Section: Methodsmentioning

confidence: 99%

Effect of orally administered bovine lactoferrin on the immune response in the oral candidiasis murine model

Takakura

Wakabayashi

Ishibashi

et al. 2004

Journal of Medical Microbiology

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Section: Methodsmentioning

confidence: 99%

Effect of orally administered bovine lactoferrin on the immune response in the oral candidiasis murine model

Takakura

Wakabayashi

Ishibashi

et al. 2004

Journal of Medical Microbiology

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“…Gour University Sagar, India. Cutaneous Candidiasis was induced on Sprague Dawley albino rats (100-150 g) by slight modification of an earlier reported procedure (Maebashi et al, 1995). Briefly, hairs on the back of the rats were removed using depilatory cream and an area of 3 × 3 cm 2 was marked.…”

Section: In Vivo Performance Studiesmentioning

confidence: 99%

Design and development of solid lipid nanoparticles for topical delivery of an anti-fungal agent

Jain

Khare

et al. 2010

Drug Delivery

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“…Candida albicans strain TIMM2640, a clinical isolate from a patient with cutaneous candidiasis (Teikyo University Institute of Medical Mycology, Tokyo) (14), was stored at Ϫ80 C in Sabouraud dextrose broth (Becton Dickinson, Md., U.S.A.) containing 0.5% yeast extract (Becton Dickinson) and 10% glycerol until the experiment was performed. The strain was grown on a Candida GS agar plate (Eiken Chemical Co., Ltd., Tokyo) at 37 C for 24 hr.…”

mentioning

confidence: 99%

A Novel Murine Model of Oral Candidiasis with Local Symptoms Characteristic of Oral Thrush

Takakura

Sato

Ishibashi

et al. 2003

Microbiology and Immunology

141

159

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A conventional and easy method to establish a murine oral candidiasis model, which has not only a stable yeast population in the oral cavity but also symptoms characteristic of oral thrush, was developed by using a sedative agent. Mice were immunosuppressed with prednisolone and were given tetracycline hydrochloride. They were orally infected with 106 viable cells of Candida albicans by means of a cotton swab and enough chlorpromazine chloride had been injected to keep them in a sedative state about for 3 hr after inoculation. From day 3 to day 7 post inoculation, 105–106 colony forming units of Candida were recovered from the oral cavity of each mouse and whitish, curd‐like patches were observed on most parts of tongue. Microscopically, germ tubes had appeared on the tongue surface. This model would be a useful experimental oral candidiasis for investigating the pathogenesis of C. albicans oral infection and the efficacy of various antifungal agents microbiologically and symptomatically.

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A novel model of cutaneous candidiasis produced in prednisolone-treated guinea-pigs

Cited by 31 publications

References 18 publications

Effect of orally administered bovine lactoferrin on the immune response in the oral candidiasis murine model

Effect of orally administered bovine lactoferrin on the immune response in the oral candidiasis murine model

Design and development of solid lipid nanoparticles for topical delivery of an anti-fungal agent

A Novel Murine Model of Oral Candidiasis with Local Symptoms Characteristic of Oral Thrush

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