A novel method for the detection of point mutation in DNA using single-base-coded CdS nanoprobes

Biosynthesis of Quantum Dots and Their Potential Applications in Biology and Biomedicine

“…As it was mentioned above, QDs can be efficiently designed for the DNA molecule detection [74,75]. First, successful exploitation of QDs for fluorescence in situ hybridization (FISH) analysis was reported in [77].…”

“…Besides, QDs can be exploited for the detection of mutations in DNA. In the study [75], the method for detecting DNA spot mutations based on CdS QD-mediated probing is reported. DNA methylation is also investigated using QDs during the PCR reaction [76].…”

Determination of total aflatoxin using cysteamine-capped CdS quantum dots as a fluorescence probe

“…There are numerous studies on the application of surface modified CdS QDs to the detection of metal ions, such as Cu 2+ , Cd 2+ , Hg 2+ , and Ag + [37] and of biomolecules such as DNA [38]. Different emission wavelengths have been reported for CdS QDs, varying from green to red [39].…”

Sensitive and selective DNA detection based on the combination of hairpin-type probe with endonuclease/GNP signal amplification using quartz-crystal-microbalance transduction

“…Several classical signal amplification strategies have been employed to develop piezoelectric transducers for sensitive detection of DNA hybridization. For these screening schemes, liposmes [34], enzymes [35], metal nanoparticles [32,36] and semiconductors [37] functioned with biomolecules were often used to intensify the frequency shift upon introduction of target DNA. Among them, due to the relatively large mass compared to target DNAs, gold nanoparticles acting as effective "mass amplifiers" display a great potential in the improvement of assay performance, especially in the detection sensitivity [38,39].…”