Search citation statements
Paper Sections
Citation Types
Year Published
Publication Types
Relationship
Authors
Journals
Background and objective: An effort-independent breath sound analysis is expected to be a safe and simple method for clinical assessment of changes in airway function. The effects of bronchoconstriction and bronchodilation on novel breath sound parameters in asthmatic children were investigated. Methods: The study population included 49 children with atopic asthma (male = 33; mean age: 10.2 years). We evaluated breath sound parameters of the highest frequency of the power spectrum (HFp), frequency limiting 50% and 99% of the power spectrum (F 50 and F 99 ) and roll-off from 600 Hz to the HFp (Slope). We also assessed new parameters obtained using the ratios of sound spectrum parameters (spectrum curve indices), such as the ratio of the third and fourth power area to the total power area (P 3 /P T and P 4 /P T ), the ratio of the third and fourth areas to the total area under the curve (A 3 /A T and B 4 /A T ) and the ratio of power and frequency at 75% of HFp and 50% of HFp (RPF 75 and RPF 50 ). This was measured before and after methacholine inhalation challenge and after β 2 agonist inhalation. Results: The parameters, F 50 and F 99 , showed no changes after methacholine inhalation. Conversely, the A 3 /A T (12.5-10.0%, P < 0.001), B 4 /A T (7.6-5.5%, P < 0.001), RPF 75 (6.7-4.0 dBm/Hz, P < 0.001) and RPF 50 (5.8-4.3 dBm/Hz, P < 0.001) were significantly decreased. These values returned to the original level after β 2 agonist inhalation. Conclusion: Spectrum curve indices indicate bronchoconstriction and bronchodilation. These parameters may play a role in the assessment of airway narrowing in asthmatic children.
Background and objective: An effort-independent breath sound analysis is expected to be a safe and simple method for clinical assessment of changes in airway function. The effects of bronchoconstriction and bronchodilation on novel breath sound parameters in asthmatic children were investigated. Methods: The study population included 49 children with atopic asthma (male = 33; mean age: 10.2 years). We evaluated breath sound parameters of the highest frequency of the power spectrum (HFp), frequency limiting 50% and 99% of the power spectrum (F 50 and F 99 ) and roll-off from 600 Hz to the HFp (Slope). We also assessed new parameters obtained using the ratios of sound spectrum parameters (spectrum curve indices), such as the ratio of the third and fourth power area to the total power area (P 3 /P T and P 4 /P T ), the ratio of the third and fourth areas to the total area under the curve (A 3 /A T and B 4 /A T ) and the ratio of power and frequency at 75% of HFp and 50% of HFp (RPF 75 and RPF 50 ). This was measured before and after methacholine inhalation challenge and after β 2 agonist inhalation. Results: The parameters, F 50 and F 99 , showed no changes after methacholine inhalation. Conversely, the A 3 /A T (12.5-10.0%, P < 0.001), B 4 /A T (7.6-5.5%, P < 0.001), RPF 75 (6.7-4.0 dBm/Hz, P < 0.001) and RPF 50 (5.8-4.3 dBm/Hz, P < 0.001) were significantly decreased. These values returned to the original level after β 2 agonist inhalation. Conclusion: Spectrum curve indices indicate bronchoconstriction and bronchodilation. These parameters may play a role in the assessment of airway narrowing in asthmatic children.
Background and objectives Using a lung sound analysis, the prognosis of asthma was investigated in infants with risk factors for asthma development by a long‐term observation. Methods A total of 268 infants were included (median age: 8 months old). The lung sound parameters (the ratio of the third and fourth area to the total area under the curve [A 3 /A T and B 4 /A T ], and the ratio of power and frequency at 50% and 75% of the highest frequency [RPF 50 and RPF 75 ]) were evaluated at the first visit. At 3 years old, using a questionnaire, we examined the relationship between the lung sound parameters and risk factors of asthma development. Results Among the 268 infants, 175 infants were in good health and 93 had a history of acute respiratory infection (ARI) within 7 days at the first visit. Among the 3‐ to 12‐month‐old infants with an ARI, the A 3 /A T , B 4 /A T values in those with a history of asthma/asthmatic bronchitis, atopic dermatitis, and atopy were smaller than in the infants without such histories. Among the 13‐ to 24‐month‐old infants with an ARI, the A 3 /A T and B 4 /A T values in those with a wheezing history were larger than in the infants without such a history. Conclusions The characteristics of the lung sounds in infants with risk factors for asthma development were demonstrated over long‐term follow‐up. Lung sound analyses may be useful for assessing the airway condition of infants.
Introduction:The reliability of a breath sound analysis using an objective method in infants has been reported.Objective: Breath sounds of infants with respiratory syncytial virus (RSV) acute bronchiolitis were analyzed via a breath sound spectrogram to evaluate their characteristics and examine their relationship with the severity. Subjects and Methods:We evaluated the inspiratory and expiratory breath sound parameters of 33 infants diagnosed with RSV acute bronchiolitis. The sound powers of inspiration and expiration were evaluated at the acute phase and recovery phase of infection. Furthermore, the relationship between the breath sound parameters and the clinical severity of acute bronchiolitis was examined.Results: Analyses of the breath sound spectrogram showed that the power of expiration as well as the expiration-to-inspiration sound ratio in the mid-frequency (E/I MF) was increased in the acute phase and decreased during the recovery phase.The E/I MF was inversely correlated with the SpO 2 and positively correlated with the severity score. Conclusion:In infants with RSV acute bronchiolitis, the sound power of respiration was large at the acute phase, significantly decreasing in the recovery phase. In 61% of participants, nonuniform, granular bands were shown in the low-pitched region of the expiratory spectrogram.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.