A novel hybrid catheter-directed technique to treat intermediate-high risk pulmonary embolism

Abstract

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Role of catheter-directed therapies in the treatment of acute pulmonary embolism. Expert opinion of the Polish PERT Initiative, Working Group on Pulmonary Circulation, Association of Cardiovascular Interventions, and Association of Intensive Cardiac Care of the Polish Cardiac Society

“…In some patients without absolute contraindications to thrombolysis, a combination (hybrid) pharmacomechanical treatment is possible, namely, thrombectomy supplemented with low-dose thrombolysis administered before, during, or after the catheter-directed procedure, especially if thrombectomy is not effective enough [40,41].…”

Catheter-directed therapy to treat intermediateand high-risk pulmonary embolism: Personal experience and review of the literature

“…To circumvent these disadvantages, another system available on the market (Penumbra Indigo ® System, Penumbra, Alameda, CA, USA) implements automatic suction, ensuring consistent and labor-free suction through an 8F catheter [ 31 , 32 ]. This system also uses a retractable separator that moves back and forth, thus facilitating thrombus fragmentation [ 33 ]. The short-term (48 h) safety and efficacy of the Penumbra Indigo ® System was confirmed in the EXTRACT-PE study [ 31 ].…”

Lightning 12: A new player in the field of pulmonary percutaneous mechanical thrombectomy

“…The recent development of advanced endovascular therapies aims to reduce PE-related morbidity and mortality [1,2]. CDMT involves devices for mechanical thrombus fragmentation and aspiration to quickly relieve the blockage and restore pulmonary blood flow with a subsequent improvement in the hemodynamic status in intermediate or high-risk PE [3,4]. The key innovations of the novel Lightning 12 system are the new CAT12 catheter, with a large 0.131'' lumen and angled tip for an additional circumferential sweep, and the lighting control unit with a pressure/flow sensor system and high-frequency valves.…”