A novel homodimeric lectin from Astragalus mongholicus with antifungal activity

Antimicrobial Activities of Lectins Extracted from Some Cultivars of Phaseolus vulgaris Seeds

“…In the present work, Table 3 shows that all the fractionated lectins of the five cultivars of Phaseolus vulgaris seeds under study had antifungal activity against Candida albicans. This conclusion agrees with that of Yan et al in 2005 that proved that lectins from Astragalus mongholicus seeds had a potent effect on Candida albicans [40].…”

Isolation and Antifungal Activity of Plant Lectins against some Plant Pathogenic Fungi

“…The lectin contents are low in some varieties and high in other varieties. The lectin contents in some parts of plants are higher, e.g., 390 and 75 mg of the purified lectin was recovered from 100 g Remusatia vivipara tubers (Bhat et al, 2010) and Astragalus mongholicus roots (Yan et al, 2005), respectively. The lectin content in non-legume plants is low, e.g., 3.3 mg lectin from 100 g Hibiscus mutabilis seeds (Lam and Ng, 2009).…”

Antimicrobial activity of lectins from Antimicrobial Activity of Lectins from Plants

“…6). Antifungal activity has been observed in other lectins where, for example Astragalus mongholicus root lectin revealed antifungal activity against various species of phytopathogenic fungi (Yan et al, 2005). Similarly with lectin from Talisia esculenta seeds inhibited the growth of Fusarium oxysporum, Colectrotrichum lindemuthianum, and Saccharomyces cerevisiae.…”

“…This effective lectin dose of around 100 µg/ 0.3 cm 2 disc is in accord with that reported for the lectin from Annona muricata seeds against the growth of Fusarium oxysporum, Fusarium solani and Colletotrichum musae (Damico, et al, 2003), and for the lectin from Astragalus mongholicus against Fusarium oxysporum, Colletorichum sp. and Drechslera turcia (Yan, et al, 2005). Other lectins, such as those from potato (Gomez, et al, 1995) and red kidney beans (Ye, et al 2001), have also been reported to exhibit antifungal activity.…”