A Novel Grading Method for Superficial Punctate Keratopathy Magnitude and Its Correlation With Corneal Epithelial Permeability

Effects of switching to SofZia-preserved travoprost in patients who presented with superficial punctate keratopathy while under treatment with latanoprost

“…Miyata et al 25 report a grading method to assess SPK based on the proportion of fl uorescein-stained area relative to the total area of the cornea and the staining density. It is, however, diffi cult to assess fi ndings in each area of the cornea with their method.…”

Therapeutic effect of umbilical cord serum eyedrops for the treatment of dry eye associated with graft-versus-host disease

“…Severity of keratoepitheliopathy was scored by multiplying the area score by the density score, and this product was used as an index of corneal surface damage. 15 The staining area was graded on a numerical scale of 0-3, with 0 representing no punctate staining, 1 representing less than one-third, 2 representing one-third to two-thirds, and 3 representing more than two-thirds staining. The staining density was also graded on a numerical scale of 0-3, with 0 representing no punctate staining, 1 representing sparse density, 2 representing moderate density, and 3 representing high density with overlapping lesions.…”

Efficacy and safety of switching to travoprost/timolol fixed-combination therapy from latanoprost monotherapy

“…The measurement time for each patient was decided upon based on the time of baseline measurement, so the measurements were performed within 2 h either before or after this time. Corneal erosion was evaluated based on the method described in a previous study [15]. In brief, two parameters of corneal erosion, area and density, were graded on a scale from A0 through to A3 and from D0 Table 1 Study protocol and parameters examined IOP intraocular pressure, GAT Goldmann applanation tonometry, BP blood pressure, PR pulse rate, BCVA best-corrected visual acuity, TTFC travoprost/timolol fixed-combination through to D3.…”