2019
DOI: 10.1016/j.snb.2019.04.028
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A novel fluorescent probe with one-excitation and dual-emission for selective and simultaneous detection of Glutathione and Arginine in NIR and blue regions

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Cited by 26 publications
(6 citation statements)
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“…The mechanism by which the acrylates work as the responsive groups to Cys is as follows: Michael addition of Cys to the acrylates to yield the thioether intermediates, which are intramolecularly cyclized to give lactams and to release free fluorophores. ,, To further rationalize the sensing mechanism of SDP-A toward Cys, we carried out the related product analysis by HRMS (ESI) and 1 H NMR. Upon addition of significant excess of Cys, the molecular ion peak ([M] + ) of the probe SDP-A , found as 425.1317 ( m / z ) (Figure S7A), almost disappeared along with appearance of two new signal peaks, corresponding to the free fluorophore SDP at 371.1212 ( m / z ) and the thioether intermediate at 546.1513 ( m / z ) (Figure S7B).…”
Section: Resultsmentioning
confidence: 99%
“…The mechanism by which the acrylates work as the responsive groups to Cys is as follows: Michael addition of Cys to the acrylates to yield the thioether intermediates, which are intramolecularly cyclized to give lactams and to release free fluorophores. ,, To further rationalize the sensing mechanism of SDP-A toward Cys, we carried out the related product analysis by HRMS (ESI) and 1 H NMR. Upon addition of significant excess of Cys, the molecular ion peak ([M] + ) of the probe SDP-A , found as 425.1317 ( m / z ) (Figure S7A), almost disappeared along with appearance of two new signal peaks, corresponding to the free fluorophore SDP at 371.1212 ( m / z ) and the thioether intermediate at 546.1513 ( m / z ) (Figure S7B).…”
Section: Resultsmentioning
confidence: 99%
“…GSH, as a non-nucleic acid and thiolated tripeptide, plays an important role in various physiological activities in eukaryotic cells of a living being, such as anti-oxidation, immunity, DNA regulation, and so forth . Therefore, the GSH level is one of the test items for the diagnosis of heart disease, Parkinson’s disease, Alzheimer’s disease, and cancer. A simple and sensitive method for GSH detection is highly expected in the routine body examinations . As we know, the oxidation of GSH can be expressed in the following equation 2 normalG normalS normalH normalG normalS normalS normalG + 2 normalH + + 2 normale …”
Section: Resultsmentioning
confidence: 99%
“…So far, fluorescence probes or sensors have been very seldom fabricated for simultaneous determination of multi-target analytes. 31,32 To our knowledge, fluorescence probes or sensors used for simultaneous determination of different types of analytes such as inorganic ions and organic compounds still have not been reported.…”
Section: Introductionmentioning
confidence: 99%