A novel dispersin protein in enteroaggregative Escherichia coli

Putative Virulence Genes and Biofilm Production Among Typical Enteroaggregative Escherichia coli Isolates from Diarrhoeic Children in Kashmir and Andhra Pradesh

“…In the present study 35.2 % isolates did not produce any quantifiable biofilm although all the strains were aggR positive. This corroborates with the findings of other workers [17,20] who also observed no correlation between aggR and biofilm formation. However, Mohamed et al [12] observed that isolates carrying aggR alone or in combination with other virulence genes were strongly associated with biofilm formation.…”

“…Most EAEC strains harbour a high molecular weight plasmid called pAA from which a fragment is used as a detection probe. The pAA also encodes several virulence factors that include fimbrial adhesions, astA (enteroaggregative heat-stable enterotoxin 1) [18], aap (dispersin protein) [20] and aatA (dispersin transporter/CVD432) [15] genes. The plasmid encoded toxins (pet) [6] and a cryptic open reading frame known as shf [4] have also been described.…”

Mecanismos de virulencia de Escherichia coli enteropatógena

“…En la colonización bacteriana actúa un complejo denominado Aat que se requiere para el transporte de una dispersina codificada por el gen aap, juntos regulados por AggR y codificados en el plásmi-do pAA. Aat media la secreción de la dispersina desde la membrana externa de la bacteria para promover la colonización de la mucosa intestinal (Figura 4a) 94,95 .…”

Expression of aggregative adherence to hela cells by Escherichia coli strains isolated from sick horses

“…The EAEC putative virulence genes described so far are located on a high molecular weight plasmid and comprise the agg and aaf operons (involved in the biogenesis of aggregative adherence fimbriae) (2,28), aggR (encoding the transcriptional activator AggR) (29), aap (formerly aspU, encoding dispersin) (34), shf (encoding a cryptic secreted protein, Shf) (9), and pet (encoding the Plasmid encoded toxin, Pet) (11). Chromosomal virulence genes have also been described in some EAEC strains, which comprise pic, encoding a Protein involved in colonization (Pic), and irp2, encoding the iron-repressible high-molecularweight protein 2 (Irp2) involved in Yersiniabactin expression (9).…”