A novel carbon/chitosan paste electrode for electrochemical detection of normetanephrine in the urine

Khamlichi, Redouan El; Bouchta, Dounia; Atia, Mounia Ben; Choukairi, Mohamed; Khalid, Riffi Temsamani; Raissouni, Ihssane; Tazi, Saloua; Ahrouch, Mohammadi; Soussi, Abdellatif; Draoui, Khalid; Chaouket, F.; Sefian, Mohammed Lamarti

doi:10.1007/s10008-018-3906-2

Cited by 11 publications

(7 citation statements)

References 43 publications

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“…In order to evaluate whether the electron transfer process of ETB at the composite modified electrode is diffusion or adsorption controlled, cyclic voltammetry was employed in the range of 10-500 mV s -1 , Figure 3. The result showed that the peak current for 50 µM ETB in 0.1 M PBS pH 7 linearly increases with the square root of scan rates in the range of 10-500 mV s -1 with the linear regression equation of I p (µA) = 5.5 (±0.1) v 1/2 (mV s -1 ) 1/2 + -2.8 (±1.5), R 2 = 0.9943, Inset of Figure 3.This relationship suggests that the electrochemical reaction of ethambutol at the NiNPs/ERGO modified electrode is mainly diffusion-controlled electrode process [22][23][24][25][26]. The relationship between the logarithm of the peak current and the logarithm of the scan rate (log I p vs log v) is also linear with the regression equation of log I p (µA) = 0.56 (±0.02) log v (mV s -1 ) + 0.60 (±0.03), R² = 0.9903.…”

Section: Effect Of Potential Scan Ratementioning

confidence: 84%

Sensitive electrochemical determination of ethambutol in pharmaceutical formulation and human urine at nickel nanoparticles/electrochemically reduced graphene oxide modified electrode

Mekassa¹,

Baker²,

Chandravanshi³

et al. 2019

Bull. Chem. Soc. Eth.

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This paper describes the application of nickel nanoparticles decorated electrochemically reduced graphene oxide modified glassy carbon electrode (NiNPs/ERGO/GCE) for the determination of ethambutol (ETB), an anti-Mycobacterium tuberculosis drug. The modified electrode showed remarkable electrocatalytic properties accompanied with a significant enhancement in the peak current response towards ETB compared to the bare electrode. The results showed that the composite modified electrode played a significant catalytic role due to the synergetic effect of NiNPs and ERGO. The NiNPs/ERGO modified electrode demonstrated excellent square wave voltammetric response towards ETB determination at the NiNPs/ERGO/GCE in the range 0.05-100 µM. The sensor demonstrated outstanding sensitivity towards ETB determination with limit of detection (LOD) and limit of quantification (LOQ) of 0.023 and 0.075 µM, respectively. The developed sensor was effectively validated for real sample study using drug formulation and urine samples which showed an acceptable recovery (99.6-109%). The electrode also exhibited good precision (RSD < 1%, n = 20), reproducibility (RSD < 1.9%, n = 3), long-term stability (92% of its initial response after two weeks) and selectivity towards interfering substances in the determination of ethambutol.

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Section: Effect Of Potential Scan Ratementioning

confidence: 84%

Sensitive electrochemical determination of ethambutol in pharmaceutical formulation and human urine at nickel nanoparticles/electrochemically reduced graphene oxide modified electrode

Mekassa¹,

Baker²,

Chandravanshi³

et al. 2019

Bull. Chem. Soc. Eth.

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“…However, electrochemical methods were primarily identified for catecholamine metabolites. One interesting example is the multiplexed detection of catecholamines and their metabolites (El Khamlichi et al., 2018; Zaytsev et al., 2020). Khamlichi et al.…”

Section: Tailored Biosensing Strategiesmentioning

confidence: 99%

“…Khamlichi et al. used a carbon/chitosan paste electrode for multiplex normetanephrine and dopamine electrochemical detection in five‐fold diluted human urine with LODs of 18.3 and 7.6 ppb, respectively (El Khamlichi et al., 2018). Zaytsev et al .…”

Section: Tailored Biosensing Strategiesmentioning

confidence: 99%

Biomarkers and biosensors for the diagnosis of noncompliant pH, dark cutting beef predisposition, and welfare in cattle

Nelis

Bose

Broadbent

et al. 2022

Comp Rev Food Sci Food Safe

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Meat quality can be affected by stress, exhaustion, feed composition, and other physical and environmental conditions. These stressors can alter the pH in postmortem muscle, leading to high pH and low‐quality dark cutting (DC) beef, resulting in considerable economic loss. Moreover, the dark cutting prediction may equally provide a measure for animal welfare since it is directly related to animal stress. There are two needs to advance on‐site detection of dark cutters: (1) a clear indication that biomarker (signature compounds) levels in cattle correlate with stress and DC outcome; and (2) measuring these biomarkers rapidly and accurately on‐farm or the abattoir, depending on the objectives. This critical review assesses which small molecules and proteins have been identified as potential biomarkers of stress and dark cutting in cattle. We discuss the potential of promising small molecule biomarkers, including catecholamine/cortisol metabolites, lactate, succinate, inosine, glucose, and β‐hydroxybutyrate, and we identify a clear research gap for proteomic biomarker discovery in live cattle. We also explore the potential of chemical‐sensing and biosensing technologies, including direct electrochemical detection improved through nanotechnology (e.g., carbon and gold nanostructures), surface‐enhanced Raman spectroscopy in combination with chemometrics, and commercial hand‐held devices for small molecule detection. No current strategy exists to rapidly detect predictive meat quality biomarkers due to the need to further validate biomarkers and the fact that different biosensor types are needed to optimally detect different molecules. Nonetheless, several biomarker/biosensor combinations reported herein show excellent potential to enable the measurement of DC potential in live cattle.

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“…Due to the advantages of a high surface area, sustainability, good conductivity, and chemical stability, porous carbon materials (PCs) have shown great potential for applications in many fields in recent year [12][13][14]. The synthetic strategies and the structures of their precursors significantly affect the final performance and application of porous carbons [15,16].…”

Section: Introductionmentioning

confidence: 99%

PtRu bimetallic nanoparticles embedded in MOF-derived porous carbons for efficiently electrochemical sensing of uranium

Cao

Sun

Wang

et al. 2020

J Solid State Electrochem

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PtRu bimetallic nanoparticles embedded in MOF-derived porous carbons (PtRu-PCs) were synthesized by first loading PtRu bimetallic nanoparticles into a UiO66-NH 2 host matrix and then going in situ carbonization at high temperatures. In the synthetic strategy, UiO66-NH 2 was used not only as a precursor to limit the aggregation and migration of PtRu bimetallic nanoparticles, but also as a self-sacrificial template to improve the conductivity. The as-prepared PtRu-PCs were characterized by SEM, TEM, XRD, and XPS. The PtRu-PC-based sensor had excellent sensitivity with a detection limit of 0.024 μM (S/N = 3). The developed method was successfully applied to real water samples with a recovery rate of 92-107%.

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A novel carbon/chitosan paste electrode for electrochemical detection of normetanephrine in the urine

Cited by 11 publications

References 43 publications

Sensitive electrochemical determination of ethambutol in pharmaceutical formulation and human urine at nickel nanoparticles/electrochemically reduced graphene oxide modified electrode

Sensitive electrochemical determination of ethambutol in pharmaceutical formulation and human urine at nickel nanoparticles/electrochemically reduced graphene oxide modified electrode

Biomarkers and biosensors for the diagnosis of noncompliant pH, dark cutting beef predisposition, and welfare in cattle

PtRu bimetallic nanoparticles embedded in MOF-derived porous carbons for efficiently electrochemical sensing of uranium

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