A novel biosensor for the detection of zearalenone family mycotoxins in milk

Välimaa, Anna-Liisa; Kivistö, Anniina; Leskinen, Piia; Karp, Matti

doi:10.1016/j.mimet.2009.10.017

Cited by 48 publications

(23 citation statements)

References 37 publications

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“…They can be carcinogenic, immunotoxic, nephrotoxic, teratogenic or act as endocrine disruptors [77,80]. Mycotoxins have been associated with a range of foodstuffs, including cereals, nuts, fruits, spices and milk, and biosensor methods have been developed for their detection in these matrices ( [82].…”

Section: Mycotoxinsmentioning

confidence: 99%

Biosensors for the analysis of microbiological and chemical contaminants in food

2012

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Increases in food production and the ever-present threat of food contamination from microbiological and chemical sources have led the food industry and regulators to pursue rapid, inexpensive methods of analysis to safeguard the health and safety of the consumer. Although sophisticated techniques such as chromatography and spectrometry provide more accurate and conclusive results, screening tests allow a much higher throughput of samples at a lower cost and with less operator training, so larger numbers of samples can be analysed. Biosensors combine a biological recognition element (enzyme, antibody, receptor) with a transducer to produce a measurable signal proportional to the extent of interaction between the recognition element and the analyte. The different uses of the biosensing instrumentation available today are extremely varied, with food analysis as an emerging and growing application. The advantages offered by biosensors over other screening methods such as radioimmunoassay, enzyme-linked immunosorbent assay, fluorescence immunoassay and luminescence immunoassay, with respect to food analysis, include automation, improved reproducibility, speed of analysis and real-time analysis. This article will provide a brief footing in history before reviewing the latest developments in biosensor applications for analysis of food contaminants (January 2007 to December 2010), focusing on the detection of pathogens, toxins, pesticides and veterinary drug residues by biosensors, with emphasis on articles showing data in food matrices. The main areas of development common to these groups of contaminants include multiplexing, the ability to simultaneously analyse a sample for more than one contaminant and portability. Biosensors currently have an important role in food safety; further advances in the technology, reagents and sample handling will surely reinforce this position.

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Section: Mycotoxinsmentioning

confidence: 99%

Biosensors for the analysis of microbiological and chemical contaminants in food

2012

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“…Metabolites could have different toxic effects than the parent mycotoxin [25,26]. More studies are needed in order to increase knowledge regarding this aspect.…”

Section: Introductionmentioning

confidence: 99%

Development and validation of a high performance liquid chromatographic–mass spectrometry method for the simultaneous quantification of 10 trichothecenes in ultra-high temperature processed cow milk

Flores-Flores

González-Peñas

2015

Journal of Chromatography A

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“…Tis sue bi o sen sors, opti cal im mu no sen sors, enzyme sen sors, elec troc he mi cal sen sors, qu artz crystal, ar ray and pla smon re so nan ce bi o sen sors ha ve been ap plied to de tect oc hra toxin, afla to xins, fu mo ni sin, and de oxyni va le nol in dif fe rent com mo di ti es. For exam ple, ze a ra le no ne and its de ri va ti ves we re de tec ted in milk pro ducts with a yeast who le-cell bi o lu mi ne scent sen sor (ge ne ti cally mo di fied Sac cha romyces ce re vi si ae), al lo wing de tec tion at na no mo lar con cen tra ti ons (Va li maa et al, 2010). Com pa red to ot her tra di ti o nal analyti cal tec hni qu es, bi o sen sors of fer the pos si bi lity to mo ni tor a lar ge num ber of sam ples thus be ing a very conve ni ent tool, that can al so be au to ma ted, for scre e ning to xins in ro u ti ne analysis.…”

Section: Bi O Sen Sorsmentioning

confidence: 99%

Detection of mycotoxins trough different analytical methods

Petkova

Sertova

2018

Zb Mat srp prir nauk

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In sti tu te of Ani mal Sci en ce Poc hiv ka 1, Ko stin brod 2232, Bul ga ria DE TEC TION OF MYCO TO XINS TRO UGH DIF FE RENT ANALYTI CAL MET HODS AB STRACT: Myco to xins are se con dary me ta bo li tes pro du ced by fun gi which can af fect a va ri ety of fe ed stuffs. The se com po unds eli cit to xi co lo gi cal ef fects which re pre sent risk for both hu mans and ani mals. The ir to xi city oc curs at very low con cen tra ti ons, the refo re the re is a need for sen si ti ve and re li a ble met hods for the ir de tec tion. This re vi ew aims to eva lu a te clas si cal and emer ging met hods for the analysis of myco to xins con cer ning the ir advan ta ges and di sa dvan ta ges. Cur rently, se ve ral sen si ti ve met hods ba sed on chro ma to graphic or im mu noc he mi cal tec hni que are com mer ci ally ava i la ble. Espe ci ally wi dely are used dif fe rent chro ma to grap hic met hods for qu an ti ta ti ve de ter mi na tion of myco to xins, in clu ding gas-chr o ma to graphy (GC) and high-per for man ce li qu id chr o ma to graphy (HPLC) co u pled with ul tra vi o let, f lu o re scen ce or MS de tec tors. Li qu id chro ma to graphy-tan dem mass spectro me try (LC-MS/MS) is used as a pro mi sing tec hni que for scre e ning, iden ti fi ca tion and qu an ti ta ti ve de ter mi na tion of a lar ge num ber of myco to xins. Im mu no me tric as says, such as enzyme-lin ked im mu no sor bent as says (ELI SA), are fre qu ently used for scre e ning pu r po ses. On the ot her hand, a va ri ety of emer ging met hods ha ve been pro po sed. They are ba sed on no vel tec hno lo gi es, in clu ding im mu noc hro ma to graphy (i.e. la te ral f low de vi ces), f lu o rescen ce po la ri za tion im mu no as says (FPIA), in fra red spec tro scopy (FT-NIR), mo le cu larly im prin ted polymers (MIPs), and op ti cal bi o sen sors. In ad di tion, du ring the last years, the hig hlight was put on na no sca le ma te ri als in clu ded in bi o sen sors, which are so me of the smart de vi ces used for de ter mi na tion of myco to xins.

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A novel biosensor for the detection of zearalenone family mycotoxins in milk

Cited by 48 publications

References 37 publications

Biosensors for the analysis of microbiological and chemical contaminants in food

Biosensors for the analysis of microbiological and chemical contaminants in food

Development and validation of a high performance liquid chromatographic–mass spectrometry method for the simultaneous quantification of 10 trichothecenes in ultra-high temperature processed cow milk

Detection of mycotoxins trough different analytical methods

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