A novel approach towards synthesis of benzothiazoles and benzimidazoles: Eosin Y-catalyzed photo-triggered C–S and C–N bond formation
Khushbu Rajput,
Vishal Singh,
Arsala Kamal
et al.
Abstract:A novel metal-free and environment-friendly approach for synthesizing the biologically important moiety benzothiazole, benzimidazole under visible light irradiation using photocatalyst Eosin Y, ethanol: water as a green solvent and atmospheric...
“…8 Heterocycles containing thiazole structures are special five-membered heterocyclic rings containing sulfur and nitrogen. 9,10 Thiazole is a precious and synthetically important framework known for its diverse biological activities. 11–13 The synthesis of phenyl thiazole compounds has garnered substantial interest in therapeutic science due to their potential pharmacological importance.…”
A groundbreaking approach has been developed for synthesizing 2,4-disubstituted thiazoles using an eco-friendly and metal-free approach. This novel method utilizes methyl aryl ketones, N-Bromo-succinimide(NBS), and thioamide in water as a...
“…8 Heterocycles containing thiazole structures are special five-membered heterocyclic rings containing sulfur and nitrogen. 9,10 Thiazole is a precious and synthetically important framework known for its diverse biological activities. 11–13 The synthesis of phenyl thiazole compounds has garnered substantial interest in therapeutic science due to their potential pharmacological importance.…”
A groundbreaking approach has been developed for synthesizing 2,4-disubstituted thiazoles using an eco-friendly and metal-free approach. This novel method utilizes methyl aryl ketones, N-Bromo-succinimide(NBS), and thioamide in water as a...
“…34 The main objective of green chemistry is to transition from traditional thermal methodologies to unconventional approaches with green solvents when synthesizing organic compounds with minimum waste. 35…”
A novel approach for the lipase-catalyzed synthesis of 2,4-disubstituted thiazoles from arylethanones and thioamide under ultrasonication in water as a green reaction medium.
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