A novel approach for biomechanical spine analysis: Mechanical response of vertebral bone augmentation by kyphoplasty to stabilise thoracolumbar burst fractures

Germaneau, Arnaud; Vendeuvre, Tanguy; Saget, M.; Doumalin, Pascal; Dupré, Jean-Christophe; Brémand, Fabrice; Hesser, Franck; Couvertier, Marien; Brèque, Cyril; Maxy, P.; Roulaud, Manuel; Monlezun, O.; Rigoard, Philippe

doi:10.1016/j.jmbbm.2016.02.002

Cited by 18 publications

(20 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With this setup, spinal specimens have been tested in flexibility from pure moment loadings according to one of the three physiological axis (sagittal, frontal or transverse) and were allowed to move unconstrained in the five uncontrolled degrees of freedom (free translations and rotations). To measure mobility of each vertebra of the specimen during the loading, 3D mark tracking technique was used (Germaneau et al 2016). This stereoscopic optical method consisted in tracking marks deposed on the vertebra, allowing the measurement of mobility of each vertebra of the segment.…”

Section: Methodsmentioning

confidence: 99%

Biomechanical analysis of different cross-link configurations spinal instrumentation systems: a preliminary study

Peltier

Germaneau

Dupré

et al. 2017

Computer Methods in Biomechanics and Biomedical Engineering

Self Cite

View full text Add to dashboard Cite

Section: Methodsmentioning

confidence: 99%

Biomechanical analysis of different cross-link configurations spinal instrumentation systems: a preliminary study

Peltier

Germaneau

Dupré

et al. 2017

Computer Methods in Biomechanics and Biomedical Engineering

Self Cite

View full text Add to dashboard Cite

“…Pure physiological moments of 65 N m 17 were applied to the superior end of the specimen through the use of a system of servo-electric test frame, wires, pulleys and dead weights ( Figure 1). Pure moments were imposed along the sagittal, frontal and transverse planes to reproduce movements of flexion-extension, lateral bending and torsion.…”

Section: Methodsmentioning

confidence: 99%

Biomechanical analysis of the thoracolumbar spine under physiological loadings: Experimental motion data corridors for validation of finite element models

Couvertier

Germaneau

Saget

et al. 2017

Proc Inst Mech Eng H

View full text Add to dashboard Cite

Biomechanical studies that involve normal, injured or stabilized human spines are sometimes difficult to perform on large samples due to limited access to cadaveric human spines and biological variability. Finite element models alleviate these limitations due to the possibility of reusing the same model, whereas cadaveric spines can be damaged during testing, or have their mechanicals behaviour modified by fatigue, permanent deformation or structural failure. Finite element models need to be validated with experimental data to make sure that they represent the complex mechanical and physiological behaviour of normal, injured and stabilized spinal segments. The purpose of this study is to characterize the mechanical response of thoracolumbar spine segments with an analytical approach drawn from experimental measurements. A total of 24 normal and fresh cadaveric thoracolumbar spine segments (T11-L3), aged between 53 and 91 years, were tested in pure flexion/extension, lateral bending and axial torsion using a specific experimental setup. Measurements of global and intervertebral angle variations were performed using three-dimensional mark tracking methods. Load/angle curves for each loading were fitted by a logarithmic approach with two coefficients. The coefficients for the functions describing the response of the spinal segments are given and constitute predictive models from experimental data. This work provides data corridors of human thoracolumbar spine motion segments subjected to pure bending in the three physiological planes. These data could be very useful to validate finite element models of the human spine.

show abstract

“…From the perspective of surgical procedure, PKP is still the least invasive and most efficient treatment for pain relief, and it is effective for the treatment of burst fractures with painful anesthesia that can instantly improve the early stability of OTLBF [16][17][18][19]. Therefore, it would be a great benefit for patients if the risk of intraspinal bone cement leakage could be reduced, or the safety of the surgery could be similar to that of compression fracture.…”

Section: Introductionmentioning

confidence: 99%

Modified percutaneous Kyphoplasty technique in the treatment of osteoporotic thoracolumbar burst fractures: could it reduce the odds of cement leakage?

et al. 2020

View full text Add to dashboard Cite

Background: Osteoporotic thoracolumbar burst fracture (OTLBF) is common in seniors. Due to the fracture of the posterior vertebra and spinal canal occupancy, the risk of cement leakage and spine injury is high in OTLBF patients, thus the application of vertebroplasty and kyphoplasty is limited in these patients. This study aims to investigate the efficacy and safety of the modified percutaneous kyphoplasty (MPKP) in the treatment of OTLBF. Methods: Clinical data of the OTLBF patients treated with MPKP and the osteoporotic thoracolumbar compression fracture (OTLCF) patients undergone PKP from January 2014 to June 2016 were collected. The key procedure of the MPKP was to fill the bone cavity with gel-foam by the first balloon inflation and to press the gel-foam by a second balloon inflation. Pain intensity, Oswestry disability index (ODI), and bone cement leakage of the patients in the two groups were analyzed. Results: In the burst fracture group, the overall spinal canal occupancy was relatively low, and the maximum occupancy was 1/3 of the sagittal diameter of the spinal canal. The surgical duration was longer in the burst fracture group (39.0 ± 5.0 min with 95% CI: 37.7, 40.3) than in the compression fracture group (31.7 ± 4.3 min with 95% CI: 31.1, 32.3), and the difference between the two groups was statistically significant (Z =-8.668 and P = 0.000). Both the Oswestry disability index (ODI) and the visual analog scales (VAS) were apparently improved, but there was no significant difference between the two groups. Cement leakage occurred in 13 out of the 53 cases (24.5%) in the burst fracture group and 35 out of the 193 cases (18.1%) in the compression fracture group, and there was no significant difference between the two groups (Z = − 1.038 and P = 0.299). Neither group had consequential symptoms, such as spinal cord lesion, pain, and numbness of the peripheral nerve. Conclusion: Similar to the efficacy of PKP in the treatment of OTLCF, MPKP efficiently reduced the cement leakage rate and improved the safety of the surgery, although it prolonged the surgical duration and introduced more surgical steps.

show abstract

A novel approach for biomechanical spine analysis: Mechanical response of vertebral bone augmentation by kyphoplasty to stabilise thoracolumbar burst fractures

Cited by 18 publications

References 45 publications

Biomechanical analysis of different cross-link configurations spinal instrumentation systems: a preliminary study

Biomechanical analysis of different cross-link configurations spinal instrumentation systems: a preliminary study

Biomechanical analysis of the thoracolumbar spine under physiological loadings: Experimental motion data corridors for validation of finite element models

Modified percutaneous Kyphoplasty technique in the treatment of osteoporotic thoracolumbar burst fractures: could it reduce the odds of cement leakage?

Contact Info

Product

Resources

About