A novel 86-bp indel of the motilin receptor gene is significantly associated with growth and carcass traits in Gushi-Anka F
            <sub>2</sub>
            reciprocal cross chickens

Liu, D; Han, Ruili; Wang, X; Li, W; Tang, S; Wang, Y; Jiang, Ruirui; Yan, Fengbin; Wang, C; Liu, X; Kang, Xin

doi:10.1080/00071668.2019.1655710

Cited by 17 publications

(10 citation statements)

References 32 publications

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“…All data for each trait obtained by statistical analysis are presented as the mean ± standard error (mean ± SE). P < 0.05 was considered to indicate statistical significance [32].…”

Section: Discussionmentioning

confidence: 99%

Detection of CNV in the SH3RF2 gene and its effects on growth and carcass traits in chickens

et al. 2020

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Background: The SH3RF2 gene is a protein-coding gene located in a quantitative trait locus associated with body weight, and its deletion has been shown to be positively associated with body weight in chickens.Results: In the present study, CNV in the SH3RF2 gene was detected in 4079 individuals from 17 populations, including the "Gushi ×Anka" F2 resource population and populations of Chinese native chickens, commercial layers, and commercial broilers. The F2 resource population was then used to investigate the genetic effects of the chicken SH3RF2 gene. The results showed that the local chickens and commercial layers were all homozygous for the wild-type allele. Deletion mutation individuals were detected in all of the commercial broiler breeds except Hubbard broiler. A total of, 798 individuals in the F2 resource group were used to analyze the effects of genotype (DD/ID/II) on chicken production traits. The results showed that CNV was associated with 2-, 6-, 10-, and 12-week body weight (P = 0.026, 0.042, 0.021 and 0.039 respectively) and significantly associated with 8-week breast bone length (P = 0.045). The mutation was significantly associated with 8-week body weight (P = 0.007) and 4-week breast bone length (P = 0.010). CNV was significantly associated with evisceration weight, leg muscle weight, carcass weight, breast muscle weight and gizzard weight (P = 0.032, 0.033, 0.045, 0.004 and 0.000, respectively). Conclusions: CNV of the SH3RF2 gene contributed to variation in the growth and weight gain of chickens.

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“…All data for each trait obtained by statistical analysis are presented as the mean ± standard error (mean ± SE). P < 0.05 was considered to indicate statistical significance [32].…”

Section: Discussionmentioning

confidence: 99%

Detection of CNV in the SH3RF2 gene and its effects on growth and carcass traits in chickens

et al. 2020

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“…All data for each trait obtained by statistical analysis are presented as the mean ± standard error (mean ± SE). P < 0.05 was considered to indicate statistical significance [30]. 0.00 0.00 0.00 0.00 1.00 1.00 0.00 0.00 1.00 1.00 0.00 0.00 1.00 1.00 GS/174 0.00 0.00 1.00 0.00 1.00 0.00 1.00 CS/144 0.00 0.00 1.00 0.00 1.00 0.00 1.00 GF /18 0.00 0.00 1.00 0.00 1.00 0.00 1.00 YY /44 0.00 0.00 1.00 0.00 1.00 0.00 1.00 LS/202 0.00 0.00 1.00 0.00 1.00 0.00 1.00 WH/216 0.00 0.00 1.00 0.00 1.00 0.00 1.00 GC/88 0.00 0.00 1.00 0.00 1.00 0.00 1.00 HL/456 0.00 0.00 1.00 0.00 1.00 0.00 1.00 LB/60 0.00 0.00 1.00 0.00 1.00 0.00 1.00…”

Section: Discussionmentioning

confidence: 99%

Detection of CNV in the SH3RF2 gene and its effects on growth and carcass traits in chickens

Jing

Wang

Cheng

et al. 2020

Preprint

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Background: The SH3RF2 gene is a protein-coding gene located in a quantitative trait locus associated with body weight, and its deletion has been shown to be positively associated with body weight in chickens. Results: In the present study, CNV in the SH3RF2 gene was detected in 4,079 individuals from 17 populations, including the “Gushi ×Anka” F2 resource population and populations of Chinese native chickens, commercial layers, and commercial broilers. The F2 resource population was then used to investigate the genetic effects of the chicken SH3RF2 gene. The results showed that the local chickens and commercial layers were all homozygous for the wild-type allele. Deletion mutation individuals were detected in all of the commercial broiler breeds except Hubbard broiler. A total of, 798 individuals in the F2 resource group were used to analyze the effects of genotype (DD/ID/II) on chicken production traits. The results showed that CNV was associated with 2-, 6-, 10-, and 12-week body weight ( P = 0.026, 0.042, 0.021 and 0.039 respectively) and significantly associated with 8-week breast bone length ( P = 0.045). The mutation was significantly associated with 8-week body weight ( P = 0.007) and 4-week breast bone length ( P = 0.010). CNV was significantly associated with evisceration weight, leg muscle weight, carcass weight, breast muscle weight and gizzard weight ( P = 0.032, 0.033, 0.045, 0.004 and 0.000, respectively). Conclusions: CNV of the SH3RF2 gene contributed to variation in the growth and weight gain of chickens.

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“…Genotype effects were analyzed by a multivariate linear model , and the differences among genotypes were compared by Benferroni's multiple comparison method . The specific analysis method referred to previous studies [18]. All data for each trait obtained by statistical analysis are presented as the mean ± standard error (mean ± SE).…”

Section: Discussionmentioning

confidence: 99%

Detection of CNV in the SH3RF2 gene in chickens and its effects on growth and carcass traits

Jing¹,

Wang²,

Cheng³

et al. 2020

Preprint

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BackgroundSH3RF2 gene was a protein-coding gene located in the quantitative trait locus associated with body weight , and its deletion was positively correlated with body weight in chickens.ResultsIn the present study, the SH3RF2 genotype of the “Gushi ×Anka” F2 resource population , as well as local chickens and commercial layers and broilers in China was detected , and the relationship between the genotype and chicken production traits was further studied by molecular biology technology. The results showed that the local chickens and commercial layers were all homozygous for the wild-type allele. In commercial broiler breeds, deletion mutation individuals were detected in all commercial broiler breeds except Hubbard breeds.In addition , 798 individuals in the F2 resource group were used to analyze the effects of different genotypes (DD\ ID\ II) on chicken production traits. The results showed that the mutation was associated with 2 , 6 , 10 , and 12-week body weight and a significant correllation with 8-week breast bone length (P<0.05);The mutation was significantly correlated with 8-week body weight and 4-week breast bone length (P<0.01).Additionally , evisceration weight , legs muscle weight , carcass weight and other significant correlations (P<0.05) and breast muscle weight and gizzard weight were significantly correlated (P<0.01).ConclusionsThe results of this study indicated that the copy number variation of the SH3RF2 gene contributed to the growth and weight gain of chickens.

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A novel 86-bp indel of the motilin receptor gene is significantly associated with growth and carcass traits in Gushi-Anka F ₂ reciprocal cross chickens

Cited by 17 publications

References 32 publications

Detection of CNV in the SH3RF2 gene and its effects on growth and carcass traits in chickens

Detection of CNV in the SH3RF2 gene and its effects on growth and carcass traits in chickens

Detection of CNV in the SH3RF2 gene and its effects on growth and carcass traits in chickens

Detection of CNV in the SH3RF2 gene in chickens and its effects on growth and carcass traits

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A novel 86-bp indel of the motilin receptor gene is significantly associated with growth and carcass traits in Gushi-Anka F 2 reciprocal cross chickens

Cited by 17 publications

References 32 publications

Detection of CNV in the SH3RF2 gene and its effects on growth and carcass traits in chickens

Detection of CNV in the SH3RF2 gene and its effects on growth and carcass traits in chickens

Detection of CNV in the SH3RF2 gene and its effects on growth and carcass traits in chickens

Detection of CNV in the SH3RF2 gene in chickens and its effects on growth and carcass traits

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A novel 86-bp indel of the motilin receptor gene is significantly associated with growth and carcass traits in Gushi-Anka F ₂ reciprocal cross chickens