A novel 1540nm light emission from erbium doped hydroxyapatite/β-tricalcium phosphate through co-precipitation method

Pham, Vuong-Hung; Van, Hoang Nhu; Tam, Phuong Dinh; Ha, Hanh Nguyen Thi

doi:10.1016/j.matlet.2016.01.002

Cited by 26 publications

(14 citation statements)

References 20 publications

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Section: Cation-substituted Hydroxyapatitesmentioning

confidence: 99%

“…Erbium (Er) is a promising REM element due to its light emission and enhancement of biological properties of HA [372,404]. A strong and stable near-infrared emission at ~1540 nm, compatible with telecommunication applications, has been observed in Er-doped (~4.4 at.%) HA synthesized by co-precipitation [404]. Alshemary et al [372] studied the in vitro bioactivity of Er-doped (2–10 at.%) HA fabricated by microwave-assisted precipitation from SBF solution, and showed the formation of a biomimetic apatite layer after 24 h of immersion.…”

Section: Cation-substituted Hydroxyapatitesmentioning

confidence: 99%

See 1 more Smart Citation

Cationic Substitutions in Hydroxyapatite: Current Status of the Derived Biofunctional Effects and Their In Vitro Interrogation Methods

et al. 2018

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High-performance bioceramics are required for preventing failure and prolonging the life-time of bone grafting scaffolds and osseous implants. The proper identification and development of materials with extended functionalities addressing socio-economic needs and health problems constitute important and critical steps at the heart of clinical research. Recent findings in the realm of ion-substituted hydroxyapatite (HA) could pave the road towards significant developments in biomedicine, with an emphasis on a new generation of orthopaedic and dentistry applications, since such bioceramics are able to mimic the structural, compositional and mechanical properties of the bone mineral phase. In fact, the fascinating ability of the HA crystalline lattice to allow for the substitution of calcium ions with a plethora of cationic species has been widely explored in the recent period, with consequent modifications of its physical and chemical features, as well as its functional mechanical and in vitro and in vivo biological performance. A comprehensive inventory of the progresses achieved so far is both opportune and of paramount importance, in order to not only gather and summarize information, but to also allow fellow researchers to compare with ease and filter the best solutions for the cation substitution of HA-based materials and enable the development of multi-functional biomedical designs. The review surveys preparation and synthesis methods, pinpoints all the explored cation dopants, and discloses the full application range of substituted HA. Special attention is dedicated to the antimicrobial efficiency spectrum and cytotoxic trade-off concentration values for various cell lines, highlighting new prophylactic routes for the prevention of implant failure. Importantly, the current in vitro biological tests (widely employed to unveil the biological performance of HA-based materials), and their ability to mimic the in vivo biological interactions, are also critically assessed. Future perspectives are discussed, and a series of recommendations are underlined.

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Section: Cation-substituted Hydroxyapatitesmentioning

confidence: 99%

Section: Cation-substituted Hydroxyapatitesmentioning

confidence: 99%

Cationic Substitutions in Hydroxyapatite: Current Status of the Derived Biofunctional Effects and Their In Vitro Interrogation Methods

et al. 2018

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“…(i) The first one, which is generally utilized due its reliability, implies the use of inorganic synthesis by different methods, such as hydrothermal [20,21], co-precipitation [22,23], or sol-gel [24]. However, these approaches are, on one hand, polluting and time-consuming, and, on the other hand, quite expensive [25,26].…”

Section: Bioha Vs Synthetic Hamentioning

confidence: 99%

Current Status on Pulsed Laser Deposition of Coatings from Animal-Origin Calcium Phosphate Sources

Duta

Popescu

2019

Coatings

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The aim of this paper is to present the current status on animal-origin hydroxyapatite (HA) coatings synthesized by Pulsed Laser Deposition (PLD) technique for medical implant applications. PLD as a thin film synthesis method, although limited in terms of surface covered area, still gathers interest among researchers due to its advantages such as stoichiometric transfer, thickness control, film adherence, and relatively simple experimental set-up. While animal-origin HA synthesized by bacteria or extracted from animal bones, eggshells, and clams was tested in the form of thin films or scaffolds as a bioactive agent before, the reported results on PLD coatings from HA materials extracted from natural sources were not gathered and compared until the present study. Since natural apatite contains trace elements and new functional groups, such as CO32− and HPO42− in its complex molecules, physical-chemical results on the transfer of animal-origin HA by PLD are extremely interesting due to the stoichiometric transfer possibilities of this technique. The points of interest of this paper are the origin of HA from various sustainable resources, the extraction methods employed, the supplemental functional groups, and ions present in animal-origin HA targets and coatings as compared to synthetic HA, the coatings’ morphology function of the type of HA, and the structure and crystalline status after deposition (where properties were superior to synthetic HA), and the influence of various dopants on these properties. The most interesting studies published in the last decade in scientific literature were compared and morphological, elemental, structural, and mechanical data were compiled and interpreted. The biological response of different types of animal-origin apatites on a variety of cell types was qualitatively assessed by comparing MTS assay data of various studies, where the testing conditions were possible. Antibacterial and antifungal activity of some doped animal-origin HA coatings was also discussed.

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“…Pham et al [ 24 ] synthesized erbium-doped hydroxyapatite using a coprecipitation method. The near-infrared luminescence emission of hydroxyapatite may be obtained definitely by doping with erbium.…”

Section: Hydroxyapatite Doped With Photoluminescent Elementsmentioning

confidence: 99%

“…The present methods for obtaining hydroxyapatite mostly include conventional template synthesis [ 12 , 13 ], wet chemical synthesis [ 14 , 15 , 16 ], hydrothermal conversion of calcium carbonate exoskeleton [ 17 , 18 , 19 ], calcination of xenogenic bone [ 20 , 21 ], solid phase reactions [ 22 ], co-precipitation reactions [ 23 , 24 , 25 ], sol–gel processes [ 26 , 27 , 28 ], biomimetic preparation [ 29 , 30 , 31 ], and pyrolysis [ 31 , 32 , 33 ]. The properties of synthetized hydroxyapatite differ based on preparation route, precursors, etc.…”

Section: Introductionmentioning

confidence: 99%

Luminescent Hydroxyapatite Doped with Rare Earth Elements for Biomedical Applications

et al. 2019

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One new, promising approach in the medical field is represented by hydroxyapatite doped with luminescent materials for biomedical luminescence imaging. The use of hydroxyapatite-based luminescent materials is an interesting area of research because of the attractive characteristics of such materials, which include biodegradability, bioactivity, biocompatibility, osteoconductivity, non-toxicity, and their non-inflammatory nature, as well their accessibility for surface adaptation. It is well known that hydroxyapatite, the predominant inorganic component of bones, serves a substantial role in tissue engineering, drug and gene delivery, and many other biomedical areas. Hydroxyapatite, to the detriment of other host matrices, has attracted substantial attention for its ability to bind to luminescent materials with high efficiency. Its capacity to integrate a large assortment of substitutions for Ca2+, PO43−, and/or OH− ions is attributed to the versatility of its apatite structure. This paper summarizes the most recently developed fluorescent materials based on hydroxyapatite, which use rare earth elements (REEs) as dopants, such as terbium (Tb3+), erbium (Er3+), europium (Eu3+), lanthanum (La3+), or dysprosium (Dy3+), that have been developed in the biomedical field.

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A novel 1540nm light emission from erbium doped hydroxyapatite/β-tricalcium phosphate through co-precipitation method

Cited by 26 publications

References 20 publications

Cationic Substitutions in Hydroxyapatite: Current Status of the Derived Biofunctional Effects and Their In Vitro Interrogation Methods

Cationic Substitutions in Hydroxyapatite: Current Status of the Derived Biofunctional Effects and Their In Vitro Interrogation Methods

Current Status on Pulsed Laser Deposition of Coatings from Animal-Origin Calcium Phosphate Sources

Luminescent Hydroxyapatite Doped with Rare Earth Elements for Biomedical Applications

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