A note on myeloperoxidation index and its correlation to the biomarker, urine trans, trans-muconic acid level, in the subjects occupationally exposed to benzene

Wiwanitkit, Viroj; Soogarun, Suphan; Suwansaksri, Jamsai

doi:10.1038/sj.leu.2403238

Cited by 2 publications

(1 citation statement)

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“…Although there are some studies reporting the influence of smoking on increase urinary ttMA 10,14 there is no application for usage as biomarker for smoking. Since the higher urinary ttMA indicates the higher occult risk for cancer, 15 the usage of urinary ttMA is recommended as a monitoring tool to follow up benzene exposure in the smokers. Specific preventive actions including smoking cessation and prevention for smokers with high urinary ttMA is recommended.…”

Section: Discussionmentioning

confidence: 99%

Monitoring of urine trans, trans-muconic acid level among smokers and non-smokers

Wiwanitkit

Suwansaksri

Soogarun

2005

Respiratory Medicine

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Smoking has contributed to various neurological, cardiovascular, and pulmonary diseases. According to carcinogens found in cigarette smog, benzene is one of the important carcinogenic compounds. The urinary trans, trans-muconic acid (ttMA) levels among a sample of 10 Thai smokers and 35 Thai non-smokers were investigated, compared and reported. The average urinary ttMA level in smokers and non-smokers were 2.19 +/- 2.32 and 0.24 +/- 0.33 mg/gCr, respectively. A significant higher urinary ttMA level among the smokers was observed (P < 0.05). Since the higher urinary ttMA indicates the higher occult risk for cancer, the usage of urinary ttMA is recommended as a monitoring tool to follow up benzene exposure in the smokers.

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Section: Discussionmentioning

confidence: 99%