A noninvasive eye fixation and computer-aided eye monitoring system for linear accelerator–based stereotactic radiotherapy of uveal melanoma

Local Tumor Control, Visual Acuity, and Survival After Hypofractionated Stereotactic Photon Radiotherapy of Choroidal Melanoma in 212 Patients Treated Between 1997 and 2007

“…Computed tomography and magnetic resonance imaging were used during image acquisition for treatment planning and during treatment delivery; online control of the eye's position was performed based on commercial thermoplastic SRT mask systems (BrainLAB, Heimstetten, Germany). These mask systems were modified to enable eye fixation and eye monitoring with an integrated light source and a mini-video camera (34). The mini-video camera was used to monitor the eye and pupil position during treatment preparation and treatment delivery.…”

“…A reliable eye fixation technique with online control to ensure successful irradiation of the tumor volume has been developed and investigated (26,34). In contrast to Gamma Knife SRT with invasive immobilization, this noninvasive fixation method more easily allows a fractionated treatment of uveal melanoma.…”

Stereotactic Photon Beam Irradiation of Uveal Melanoma: Indications and Experience at the University of Vienna since 1997

“…Treatment planning: Treatment planning and treatment performance of uveal melanoma at a linac were based on a commercial thermoplastic stereotactic head mask (BrainLAB, Heimstetten, Germany), which was modified to enable eye fixation and eyemonitoring [6]. The used fixation system is CT and MRI compatible and the software provides a comparison of treatment preparation and treatment delivery information.…”

“…Since 1997, at the Medical University of Vienna, patients with uveal melanoma have been treated with 3D stereotactic photon beam radiotherapy. Special fixation-and eye-monitoring systems have been developed to perform a local treatment which provides high local tumor control with acceptable long term side effects [6,7].…”

Noninvasive referencing of intraocular tumors for external beam radiation therapy using optical coherence tomography: A proof of concept

“…In the past, different approaches have been applied including suction devices, 9 retro-or parabulbar anaesthesia, 10 or active fixation of light points. [11][12][13][14] Suction devices are very uncomfortable and may cause damage to the anterior eye segment. Local anaesthesia is associated with discomfort for the patient and induces displacement of the eyeball in the orbit.…”