AʼNondislodgeable” Endoprosthesis for Nonsurgical Drainage of the Biliary Tract

Abstract

In patients with obstructive jaundice, biliary decompression can be achieved by an endoprosthesis inserted by a percutaneous transhepatic approach. The prosthesis sometimes becomes dislodged and thus additional percutaneous transhepatic procedures may be required. To avoid this problem, a nondislodgeable endoprosthesis has been developed. The prosthesis is constructed with a layer of biocompatible material (hydrogel) on its surface. The hydrogel is located in grooves around the endoprosthesis and has the ability to absorb liquid, which increases its size. By placing the rings of hydrogel on either side of the obstruction, dislodgement of the prosthesis can be prevented. The nondislodgeable endoprosthesis has been inserted into 11 patients with biliary obstructions due to malignant strictures. No dislodgement has occurred and the established internal drainage reduced serum bilirubin levels without any major complications.

Proximal stenosis of the bile ducts: Results with a new surgical endoprosthesis

“…Until now, the endoprostheses used for the intubation of the biliary tract were designed for either endoscopic [14] or percutaneous [15,16] insertion. Despite the good results obtained by Huguet and Georges et al [1,2], with tubes left in situ, a specific endoprosthesis designed for surgical intubation of the biliary tract did not exist.…”

Hydrogels in Regenerative Medicine

“…Here, the hydrogel ring located in the grooves around the endoprosthesis is placed on both sides of the occlusion. The swelling of the rings prevents the device from coming out of its place, thus protecting the internal drainage [141].…”