A New Solution to a Rare Problem of Implantable Cardiac Device Hypersensitivity

Al-Zakhari, Rana; Aljammali, Safa; Isber, Ryan; Grigos, Angela; Isber, Nidal

doi:10.7759/cureus.17882

Cited by 2 publications

(13 citation statements)

References 6 publications

(11 reference statements)

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“…Clinical presentation can mimic a PM infection and, therefore, can lead to multiple device replacements and repositions and to unnecessary prolonged antibiotic therapy. 10,13,14 Hypersensitivity reaction to a component of device usually manifests as a local contact dermatitis but occasionally may be generalized, especially if the allergy is to a component of the catheters. 10,15 Therefore, it can be manifested with pruritus, pain, cutaneous eruption, erythema, and swelling at the site of PM insertion (Figure 1).…”

Section: Clinical Presentation Of Cieds Allergymentioning

confidence: 99%

“…10,13,14 Hypersensitivity reaction to a component of device usually manifests as a local contact dermatitis but occasionally may be generalized, especially if the allergy is to a component of the catheters. 10,15 Therefore, it can be manifested with pruritus, pain, cutaneous eruption, erythema, and swelling at the site of PM insertion (Figure 1).…”

Section: Clinical Presentation Of Cieds Allergymentioning

confidence: 99%

“…31,34 In another case, however, the allergy was effectively treated with a coating with antibiotic-coated envelopes. 10 Other methods described include wrapping the generator or cables in a sheet of polytetrafluoroethylene. 35 In another case, they decided to switch to an epicardial pacing system keeping the same components.…”

Section: Diagnosismentioning

confidence: 99%

“…It would be a type IV hypersensitivity reaction according to the classification of Gell and Coombs, mediated by T‐cell lymphocytes 9 . In 1997, the incidence was estimated to be about 571 per 1 million 10 and annual incidence of 1–2 per 100 000 patients 11 . In more recent studies, the prevalence of delayed‐type hypersensitivity after implantation of CIEDs has been estimated to be approximately 1.5%–2.5% 12 .…”

Section: Introductionmentioning

confidence: 99%

“…In cases where a hypersensitivity reaction to a generator component is suspected, there have been reports describing the resolution of symptoms with the use of a gold‐coated PM in place of titanium 31,34 . In another case, however, the allergy was effectively treated with a coating with antibiotic‐coated envelopes 10 …”

Section: Introductionmentioning

confidence: 99%

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Cardiac implantable electronic devices (CIEDs) and allergy

Ruvo

Petrungaro²,

Luca

et al. 2023

Journal of Arrhythmia

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Thousands of implantable pacemakers (PMs) and implantable cardioverter defibrillators, which are referred to as cardiac implantable electronic devices (CIEDs), are implanted in the world each year. PMs provide life-saving therapy for the treatment of bradyarrhythmias; defibrillators also provide treatment for ventricular tachyarrhythmias and sudden arrhythmic death. The prevalence and incidence of PMs implantation are unknown in many countries but there is continued growth due to increased life expectancy and an increasing aging population. However, there is great variability between richer and developing countries. In Europe, there are countries such as France, Italy, and Sweden in which the rate of PMs implantation is >1000 implants per million people, whereas others, such as Azerbaijan, Bosnia and Herzegovina, and Kyrgyzstan, with <25 PM implants per million people. Currently, the estimated number of patients undergoing PM implantation globally is 1 million devices per year. 1 Regarding the number of ICD implantations, clinical research conducted by the European Heart Rhythm Association in the European Society of Cardiology countries reports that the average number of ICD implantations per million inhabitants in 2015 was 102. The European country with the highest number of implantations was Germany with 358 per million population, followed by San Marino −242-and Italy −238-, whereas the lowest implantation rate was in Ukraine with only one per million population. 2 | Implant complicationsDevice implantation surgery is associated with a risk of complications, especially in the perioperative phase, although a considerable risk remains even in the long term. The most common ones are device infection, lead dislocation and malposition, surgical wound hematoma, and pneumothorax. 1 In the MOST study, complication

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Section: Clinical Presentation Of Cieds Allergymentioning

confidence: 99%

Section: Clinical Presentation Of Cieds Allergymentioning

confidence: 99%

Section: Diagnosismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Cardiac implantable electronic devices (CIEDs) and allergy

Ruvo

Petrungaro²,

Luca

et al. 2023

Journal of Arrhythmia

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Contact allergy to subcutaneous implantable cardioverter defibrillator in a child with Brugada syndrome

Ciriello,

Colonna,

Correra

et al. 2024

Pacing Clinical Electrophis

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Allergic reactions to components of cardiac implantable electronic devices are rare and often go undiagnosed, which can lead to a misdiagnosis of device infection. Contact allergy to subcutaneous implantable cardioverter defibrillator (S‐ICD) is extremely rare. In this report, we present a case of cobalt‐related contact allergy in a pediatric patient with Brugada syndrome who underwent S‐ICD implantation.

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A New Solution to a Rare Problem of Implantable Cardiac Device Hypersensitivity

Abstract: Al-Zakhari et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Cited by 2 publications

References 6 publications

Cardiac implantable electronic devices (CIEDs) and allergy

Cardiac implantable electronic devices (CIEDs) and allergy

Contact allergy to subcutaneous implantable cardioverter defibrillator in a child with Brugada syndrome

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