A new selective fluorescent chemosensor for Cu(II) ion based on zinc porphyrin-dipyridylamino

Plasmon‐Enhanced Fluorescence‐Based Core–Shell Gold Nanorods as a Near‐IR Fluorescent Turn‐On Sensor for the Highly Sensitive Detection of Pyrophosphate in Aqueous Solution

“…Cu 2+ was a well‐known highly efficient fluorescent quencher due to its paramagnetic properties via electron or energy transfer . Cu 2+ could form complexes with porphyrin molecules, resulting in the fluorescence quenching . Recent research demonstrated that Cu 2+ complexes showed strong affinity toward PPi, and could be available for design PPi sensors using displacement strategies .…”

Toward a molecular understanding of the photosensitizer–copper interaction for tumor destruction

“…On the other hand, fluorescence enhancing was observed for the supramolecular self-assembly of the porphyrin-fluorescein hybrid with copper(II) compounds of the 5-(p-amino-phenyl)-10,15,20-triphenylporphyrin system (Lu et al 2004). Furthermore, in another study, upon adding various metal ions (e.g., Na 2+ , Cr 3+ , Mg 2+ , Fe 2+ , Mn 2+ , Ni 2+ , Ag+, Zn 2+ , Co 2+ , Cd 2+ , Hg 2+ , and Cu 2+ ) to zinc porphyrin-dipyridylamino solutions, only copper showed a high selectivity to the PS, causing quenching of the fluorescence signal upon binding with the PS (Weng et al 2007). Copper plays an essential role in tumor progression and development (Di Vaira et al 2004).…”

“…It has been reported that there is a dark cytotoxicity when the amino group of some PSs binds on the periphery of the PS molecule and that this dark toxicity is absent when the amino group is removed (Poland and Knutson 1982;Rancan et al 2005). In another study (Weng et al 2007), the binding site was also defined at the peripheral ring where the nitrogen atom is located. This behavior can be explained by defining the reaction of coordinate bond as follows:…”

“…As a result, copper is bound to the PS molecule on the periphery where the nitrogen atom is positioned; therefore, PS becomes cationic with charge of 2e (e is the electron charge). Since these PSs were reported to have dark cytotoxicity (Rancan et al 2005;Weng et al 2007), it can be concluded that static quenching, which is a physical process, can, at least partially, underlie this cytotoxicity. For many cases of coupling when static quenching occurs in the absence of light, the dynamic quenching of coupling also occurs in the presence of light (Lakowicz 1999;Al-Omari and Al-Noaimi 2010).…”

Using 5,10,15,20-tetra(4-nitrophenyl)porphyrin as a fluorescent chemosensor to determine Ru3+

“…The porphyrin macrocycles have been used as fluorophore owing to their high absorption coefficient in the visible range, tunable fluorescence emission, large Stoke shift, which can minimize fluorescence background and high photoand chemical-stability [17][18][19] . In addition, porphyrin metallation can be used as a method to determine metal cations when emission properties of metalloand free base-porphyrin are significantly different 20 .…”