A New Score for Predicting Neonatal Very Low Birth Weight Mortality Risk in the NEOCOSUR South American Network

Abstract

in infants with birth weight 500 to 1500 g were employed. A testing sample and crossvalidation techniques were used to validate a statistical model for risk of in-hospital mortality. The new risk score was compared with two existing scores by using area under the receiver operating characteristic curve (AUC). RESULTS:The new NEOCOSUR score was highly predictive for in-hospital mortality (AUC ¼ 0.85) and performed better than the Clinical Risk Index for Babies (CRIB) and the NICHD risk models when used in the NEOCOSUR Network. The new score is also well calibrated F it had good predictive capability for in-hospital mortality at all levels of risk (HL test ¼ 11.9, p ¼ 0.85). The new score also performed well when used to predict in hospital neurological and respiratory complications. CONCLUSIONS:A new and relatively simple VLBW mortality risk score had a good prediction performance in a South American network population. This is an important tool for comparison purposes among NICUs. This score may prove to be a better model for application in developing countries.

Neonatal near miss and mortality: factors associated with life-threatening conditions in newborns at six public maternity hospitals in Southeast Brazil

“…Risk factors such as maternal characteristics (low income, low schooling, extreme age group, and hypertensive diseases of pregnancy), newborn characteristics (prematurity, low birth weight, asphyxia, congenital malformation, infection), and obstetric/neonatal care issues are frequently investigated in neonatal mortality studies 1,2,3,4 .…”

Development and validation of the Neonatal Mortality Score-9 Mexico to predict mortality in critically ill neonates

“…Perinatal outcome measures did not prove to be useful in our prognostic model; this phenomenon had already been contemplated by the SNAP (Score for Neonatal Acute Physiology) scale in 2001, 20 but ours differs from the NEOCOSUR scale, 8 that does include prenatal variables.…”

“…There are scales or scores used at an international level: 5 SNAPPE 6 (Score for Neonatal Acute Physiology Perinatal Extension), CRIB II 7 (Clinical Risk Index for Babies Score) and NEOCOSUR (Neonatal del Cono Sur). 8 They are mostly used in premature infants weighing under 1500 g. T h i s s t u d y p r o p o s e s t h e development and validation of a score to predict mortality in critically ill newborn infants, without excluding those weighing above 1500 g, based on the inclusion of new prognostic factors.…”

Perinatal factors associated with neonatal mortality in very low birth weight infants: a multicenter study

“…12 Briefly, the NEOCOSUR score estimates the probability of death of VLBW infants considering their BW, GA, Apgar score at 5 minutes, life-threatening congenital malformations, antenatal corticosteroids, and gender. The mortality tendency analysis was done using a linear regression model.…”