A new Rhodamine B-based ‘on–off’ chemical sensor with high selectivity and sensitivity toward Fe3+ and its imaging in living cells

Bao, Xiaofeng; Shi, Jiaxin; Nie, Xuemei; Zhou, Baojing; Wang, Xinlong; Zhang, Luyong; Liao, Hong; Pang, Tao

doi:10.1016/j.bmc.2014.06.054

Cited by 66 publications

(28 citation statements)

References 52 publications

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“…Synthesis of compound 1 was according to the reported procedure. 36 N-(2-(3', 6'-bis (diethylamino)-3 2+ , in deionized water were prepared. The stock solution of RBMAB (10 mol L -1 ) was prepared in ethanol/PBS (3:2; v/v; 1.2 mmol L -1 , pH 7.2).…”

Section: Materials and Instrumentationmentioning

confidence: 99%

“…Compound 1 was prepared in a 92% yield from commercially available rhodamine B and ethane-1,2-diamine. 36 RBMAB was prepared in a 71.8% yield by the reaction of 3-aminobenzoic acid with 1.5 equiv of compound 1, 1.5 equiv of DCC, 1.5 equiv of HOBt and 1.5 equiv of triethylamine in DMSO for 12 h. The structure of RBMAB was confirmed by 1 H NMR, 13 C NMR and HRMS (Supporting materials).…”

Section: Synthesis Of Rbmabmentioning

confidence: 99%

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A new Rhodamine B derivative RBMAB as a highly selective and sensitive chemosensor for Fe3+ with low detection limit

Shen¹,

Wang²,

Chen³

et al. 2016

Quim. Nova

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A new Rhodamine B derivative RBMAB, namely 3-amino-N-(2-(3',6'-bis (diethylamino)-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl) ethyl)benzamide, was designed, synthesized and structurally characterized to develop a chemosensor. The studies show that RBMAB exhibits high selectivity toward Fe 3+ among many other metal cations in an ethanol-H 2 O (3:2, v/v, PBS buffer, 1.2 mmol L -1 , pH 7.2) solution. It has a low detection limit of 0.021μm. Fluorescence microscopy experiments further demonstrate that RBMAB can be used as a fluorescent probe to detect Fe 3+ in living cells.

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Section: Materials and Instrumentationmentioning

confidence: 99%

Section: Synthesis Of Rbmabmentioning

confidence: 99%

A new Rhodamine B derivative RBMAB as a highly selective and sensitive chemosensor for Fe3+ with low detection limit

Shen¹,

Wang²,

Chen³

et al. 2016

Quim. Nova

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show abstract

“…However, only a few sensors for Fe 3? have been reported despite its importance in many biochemical processes at the cellular level [24][25][26][27][28]. Herein, we report a new rhodamine-based ''turn-on'' fluorescent chemosensor 2 (Scheme 1) for Fe 3?…”

Section: Introductionmentioning

confidence: 98%

A rhodamine-based “turn-on” fluorescent probe for Fe3+ in aqueous solution and its application in bioimaging

Liu

et al. 2015

Monatsh Chem

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A novel colorimetric and off-on fluorescent chemosensor which contained a strong electron-withdrawing group was synthesized. As expected, the chemosensor exhibited high selectivity and excellent sensitivity in both absorbance and fluorescence detection of Fe 3? (H (CH 3 OH, H 2 O) = 3/7, 1 mM Tris-HCl buffer, pH = 7.40). Upon addition of Fe 3? , the solution of the chemosensor resulted in a color change from colorless to obvious pink. These significant changes in color could be used for naked-eye detection. Furthermore, fluorescence imaging experiments of Fe 3? ions in living MGC-803 cells demonstrated its value of practical applications in biological systems. Graphical abstract

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“…However, both its deficiency and excess accumulation are associated to the various disorders such as anemia, damage to the liver and kidney and Alzheimer's and Parkinson's diseases [7][8][9][10]. Indeed, there are very promising Fe 3+ -fluorescent sensor which were prepared in a simple procedure and were able to detect this ion in trace amount [11][12][13][14]. Since Fe 3+ is mostly occurred in aqueous media, it is of great importance that the sensor be able of on-line detection of this ion directly in water.…”

Section: Introductionmentioning

confidence: 99%

A Novel Naphthalene-Immobilized Nanoporous SBA-15 as a Highly Selective Optical Sensor for Detection of Fe3+ in Water

2015

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A novel organic-inorganic hybrid optical sensor (SBA-NCO) was designed and synthesized through immobilization of isocyanatopropyl-triethoxysilane and 1-amino-naphthalene onto the surface of SBA-15 by post-grafting method. The characterization of materials using XRD, TEM, N2 adsorption-desorption, and FT-IR techniques confirmed the successful attachment of organic moieties and preserving original structure of SBA-15 after modification step. Fluorescence experiments demonstrated that SBA-NCO was a highly selective optical sensor for the detection of Fe(3+) directly in water over a wide range of metal cations including Na(+), Mg(2+), Al(3+), K(+), Ca(2+), Cr(3+), Mn(2+), Fe(2+), Co(2+), Ni(2+), Cu(2+), Zn(2+), Cd(2+), Hg(2+), and Pb(2+) in a wide pH values.

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A new Rhodamine B-based ‘on–off’ chemical sensor with high selectivity and sensitivity toward Fe3+ and its imaging in living cells

Cited by 66 publications

References 52 publications

A new Rhodamine B derivative RBMAB as a highly selective and sensitive chemosensor for Fe3+ with low detection limit

A new Rhodamine B derivative RBMAB as a highly selective and sensitive chemosensor for Fe3+ with low detection limit

A rhodamine-based “turn-on” fluorescent probe for Fe3+ in aqueous solution and its application in bioimaging

A Novel Naphthalene-Immobilized Nanoporous SBA-15 as a Highly Selective Optical Sensor for Detection of Fe3+ in Water

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