A new Rhodamine B derivative RBMAB as a highly selective and sensitive chemosensor for Fe3+ with low detection limit

Abstract

A new Rhodamine B derivative RBMAB, namely 3-amino-N-(2-(3',6'-bis (diethylamino)-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl) ethyl)benzamide, was designed, synthesized and structurally characterized to develop a chemosensor. The studies show that RBMAB exhibits high selectivity toward Fe 3+ among many other metal cations in an ethanol-H 2 O (3:2, v/v, PBS buffer, 1.2 mmol L -1 , pH 7.2) solution. It has a low detection limit of 0.021μm. Fluorescence microscopy experiments further demonstrate that RBMAB can be used as a fluorescent probe to detect Fe 3+ in living cells.

Phenothiazine–rhodamine‐based colorimetric and fluorogenic ‘turn‐on' sensor for Zn2+ and bioimaging studies in live cells

“…When pH was adjusted to between 1 and 5, the fluorescence intensity of the PTRH was reputedly enhanced due to spirolactam ring opening in the amide form of rhodamine. These results clearly indicated that the PTRH sensor was insensitive to pH ranging from 5 to 14 and may work under approximately physiological conditions with very low background fluorescence …”

Fabrication of Multifunctional Stimuli‐Responsive Hydrogels Susceptible to both pH and Metal Cation for Visual Detections

“…To demonstrate facile functionalization of the obtained hydrogel to provide a pH‐ and metal ion–sensing platform, a rhodamine derivative (RHB‐NH 2 ) was chosen. It is well established that the rhodamine moiety exhibits colorimetric response to acidic pH, as well as toward certain metal ions like Fe 3+ . This is easily observable by naked eye, as well as through UV–vis spectroscopy.…”

“…It is well established that the rhodamine moiety exhibits colorimetric response to acidic pH, as well as toward certain metal ions like Fe 3+ . [39][40][41][42][43][44][45][46] This is easily observable by naked eye, as well as through UV-vis spectroscopy. The spectra of RHB-NH 2 taken at pH 3.3 (in acetate buffer) and pH 7.4 (phosphate buffer) shows a strong absorbance peak at 561 nm only at acidic pH ( Figure S7, Supporting Information).…”