A new pacemaker algorithm for the treatment of atrial fibrillation

Long‐Term Effects of Dynamic Atrial Overdrive Pacing on Sleep‐Related Breathing Disorders in Pacemaker or Cardioverter Defibrillator Recipients

“…All patients received Identity™ DR dual chamber pacemakers (St. Jude Medical) or Epic+™ DR or Atlas+™ DR ICD (St. Jude Medical) with the AFx™ algorithm and bipolar pacing leads compatible with these devices. The algorithm provides dynamic atrial overdrive pacing above the intrinsic atrial rate for prevention of atrial fibrillation 5 . We used this algorithm to ensure a high percentage of atrial pacing at a rate 5–10 bpm above the patient's intrinsic rhythm, limited by the maximum sensor rate.…”

Prospective Randomized Study to Assess the Efficacy of Site and Rate of Atrial Pacing on Long-Term Progression of Atrial Fibrillation in Sick Sinus Syndrome

“…28 The continuous atrial pacing algorithm used in this study automatically overdrives the sinus rate by 5-10 bpm up to 130/minute, and appears to be durable over time. 29 Despite this, long-term progression to persistent AF was not suppressed over backup pacing. Consistent with our findings, recent data from ASymptomatic atrial fibrillation and Stroke Evaluation in pacemaker patients and the atrial fibrillation Reduction atrial pacing Trial (ASSERT) also showed that continuous atrial overdrive pacing did not prevent new-onset AF in a pacemaker population.…”

Atrial fibrillation and quality of life after pacemaker implantation for sick sinus syndrome: Data from the Mode Selection Trial (MOST)

“…15 The CTOPP study randomized N2,500 patients with symptomatic bradycardia to ventricular or "physiologic" (dual-chamber or atrial) pacing. 3 Physiologic pacing was associated with a decrease in AF during the trial, 3,13 but there were no significant differences in QOL detected between treatment arms, 16 although the specific effect of AF on QOL has not been reported.…”