A New Method for Synthesis of 2,4,5-Triaryl-1H-Imidazole Derivatives using SiO2-NaHSO4 under Solvent-free Conditions

Abstract

A mixture of benzyl, aromatic aldehyde and ammonium acetate in presence of SiO 2 -NaHSO 4 under solvent-free condition were converted to 2,4,5-Triaryl-1H-Imidazoles. The short reaction time, cleaner reaction, and easy workup make this protocol practical and economically attractive.

Copper borate (CuB4O7)-promoted multi-component green synthesis of 2,4,5-triarylimidazole derivatives and evidence of in situ conversion of copper borate (CuB4O7) into Cu(OAc)2 in the presence of NH4OAc

“…Comparisons of efficacy of CuB 4 O 7 with those of the reported catalysts 70–91 for the synthesis of 2,4,5-trisubstituted imidazole have shown that the present system involving CuB 4 O 7 has proven to be more efficient in terms of the short reaction time, milder reaction condition, and product yields (Table 4).…”

An Efficient One-Pot Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions

“…30(1), 355-357 (2014) Although numerous methods are capable of affecting these synthesis has been previously reported [9][10][11][12][13][14][15][16][17][18] . Previously, we have synthesized a number of heterocyclic compounds [19][20][21][22][23][24][25][26][27][28][29][30] . Herein we report some of DHPMs at one pot reaction, environmentally friendly with high yields and easy separation (Scheme 1).…”

One-Pot Synthesis of 1,8-Dioxo-octahydroxanthene Derivatives Using Zn(NO3)2 under Solvent-free Conditions

“…Recently, several improved methodologies have been developed that use triethylbenzyl ammonium chloride 10 , p-dodecyl benzenesulfonic acid 11 , phosphomolybdic acid supported on silica gel 12 , sulfonic acid on silica gel 13 , HClO 4 -SiO 2 14 and ZnO 15 among others. Previously, we have synthesized a number of heterocyclic compounds [16][17][18][19][20][21][22][23][24][25][26] .…”