A New Method for Quantitative Ultrasound Measurements at Multiple Skeletal Sites

Barkmann, Reinhard; Kantorovich, E.; Singal, Chaim; Hans, Didier; Genant, Harry K.; Heller, Martin; Glüer, Claus-Christian

doi:10.1385/jcd:3:1:001

Cited by 171 publications

(82 citation statements)

References 16 publications

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“…Many authors have asked the question whether BMD of the mandible reflects the state of the skeleton and hence may be a marker of osteopenia or osteoporosis (2). Earlier studies by Von Wowern et al (27) with the use of older methods of SPA (singlephoton absorptiometry) and DPA (dual-photon absorptiometry) for the assessment of bone spine, forearm and mandible bones denied the existence of a correlation between them.…”

Section: Discussionmentioning

confidence: 99%

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Interrelationships between Morphometric, Densitometric, and Mechanical Properties of Mandible in 6-month-old Male Pigs

Tymczyna

Bachanek

Tatara

et al. 2012

Bulletin of the Veterinary Institute in Pulawy

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The aim of the study was to evaluate interrelationships between final body weight, and morphometric, densitometric, and mechanical properties of the mandible in 6-month-old Polish Large White pigs exposed to dexamethasone and nanocalcium. The study was performed on 27 males, castrated on the 28 th d after weaning, and reared until the age of 6 months, after which the animals were slaughtered, and the mandible was obtained. The pigs were divided into four experimental groups: animals given per os nanopartical calcium, animals injected with dexamethasone, animals given both nanopartical calcium per os and dexamethasone injections, and animals injected with placebo. After the slaughter, morphological properties of the mandible such as bone weight and length were determined. Using computed tomography technique, volumetric bone mineral density (vBMD) of the cortical bone (Cd), mean volumetric bone mineral density (MvBMD), and total bone volume (Bvol) of whole mandible were measured. Areal bone mineral density (BMD) and bone mineral content were evaluated with the use of dual-energy X-ray absorptiometric method. Using three-point bending test, mechanical parameters such as maximum elastic strength (Wy) and ultimate strength (Wf) of mandible were estimated. Pearson's correlation coefficient (r) was determined between all the investigated variables. The obtained results showed a significantly positive correlation between body weight and mandible weight, mandible length, Bvol, Cd, BMD, BMC, Wy, and Wf. However, statistically insignificant correlations of MvBMD and body weight, mandible weight, mandible length, and Bvol were observed. Furthermore, Bvol and Cd were not found to be significantly correlated. In conclusion, this study showed numerous positive correlations between final body weight and densitometric, morphometric, and mechanical properties of the mandible. This bone of pigs may be used as an attractive model for further investigation on metabolic response of the skeleton to physiological, nutritional, toxicological, and pharmacological factors influencing bone tissue metabolism.

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Section: Discussionmentioning

confidence: 99%

“…Determination of bone mineral content (BMC) and bone mineral density (BMD) has become essential in investigation of the calcium metabolism and associated bone diseases. BMD is defined as BMC divided by the area of interest, expressed in g/cm 2 . It has been intensely discussed in which part of the skeleton the bone mass should be determined.…”

mentioning

confidence: 99%

Interrelationships between Morphometric, Densitometric, and Mechanical Properties of Mandible in 6-month-old Male Pigs

Tymczyna

Bachanek

Tatara

et al. 2012

Bulletin of the Veterinary Institute in Pulawy

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“…This emitter and receiver configuration is typical one in ultrasonic axial transmission devices for characterizing the cortical layer of bone. When using the axial transmission technique, the earliest event or wavelet (also called by First Arriving Signal, FAS) of the multicomponent signal recorded at the receivers has been the most often investigated because it is considered as a relevant index of bone status [18,1,8]. In this work, the quantity of interest to be studied will be the FAS velocity.…”

Section: Governing Equations and Numerical Methodsmentioning

confidence: 99%

Ultrasound Wave Propagation in a Stochastic Cortical Bone Plate

Naı̈li

Nguyen

et al. 2014

Advances in Intelligent Systems and Computing

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Abstract. Ultrasonic guided-wave technologies are powerful nondestructive testing techniques to characterize bone material. This work aims to evaluate the effect due to spatial heterogeneity of bone material properties on its ultrasound response using axial transmission technique. A probabilistic model is introduced to describe the mechanical behavior of bone material. The numerical results focused on studying of FAS (First Arriving Velocity) showing that this quantity strongly depends on the dispersion induced by statistical fluctuations of stochastic elasticity field.

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“…30 Precision results for the Sunlight Omnisense have been reported to range from 0.2 to 1.48% depending on the anatomical site measured. [31][32][33] As a result of the poor precision of QUS in comparison to DXA, optimisation of measurements to reduce precision errors is of utmost importance. Parametric imaging has been introduced on some calcaneal scanners in an attempt to improve precision.…”

Section: Precisionmentioning

confidence: 99%

Quantitative ultrasound and bone health

Knapp¹

2009

Salud pública Méx

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A New Method for Quantitative Ultrasound Measurements at Multiple Skeletal Sites

Cited by 171 publications

References 16 publications

Interrelationships between Morphometric, Densitometric, and Mechanical Properties of Mandible in 6-month-old Male Pigs

Interrelationships between Morphometric, Densitometric, and Mechanical Properties of Mandible in 6-month-old Male Pigs

Ultrasound Wave Propagation in a Stochastic Cortical Bone Plate

Quantitative ultrasound and bone health

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