A new method for quantification of aortic stiffness in vivo using magnetic resonance elastography (MRE): a translational study from sequence design to implementation in patients

Clough, Rachel E.; Holub, Ondrej; Fok, Henry; Gaddum, Nicholas; Alastruey, Jordi; Sinkus, Ralph

doi:10.1186/1532-429x-17-s1-o42

Cited by 3 publications

(1 citation statement)

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“…Sinkus et al estimated the shear modulus of the interventricular septum by imaging the shear wave propagation induced by aortic valve closure (AVC) 17 . Recently, Clough et al performed aortic MRE on 8 healthy volunteers and 15 patients with hypertension using AVC as the wave generating source 27 . One of the advantages of intrinsically induced mechanical waves is that it does not suffer from the insufficient wave penetration encountered with an external driver when imaging small, deep regions of interest with high frequency.…”

Section: Mre Driver Systemmentioning

confidence: 99%

Advances and Future Direction of Magnetic Resonance Elastography

Dong

White

Kolipaka

2018

Topics in Magnetic Resonance Imaging

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The mechanical properties of soft tissues are closely associated with a variety of diseases. This motivates the development of elastography techniques in which tissue mechanical properties are quantitatively estimated through imaging. Magnetic resonance elastography (MRE) is a non-invasive phase-contrast MR technique where shear modulus of soft tissue can be spatially and temporally estimated. MRE has recently received significant attention due to its capability in non-invasively estimating tissue mechanical properties, which can offer considerable diagnostic potential. In this work, recent technology advances of MRE, its future clinical applications, and the related limitations will be discussed.

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Section: Mre Driver Systemmentioning

confidence: 99%

Advances and Future Direction of Magnetic Resonance Elastography

Dong

White

Kolipaka

2018

Topics in Magnetic Resonance Imaging

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Arterial pulse attenuation prediction using the decaying rate of a pressure wave in a viscoelastic material model

Menacho

Rotllant

Molins

et al. 2017

Biomech Model Mechanobiol

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The present study examines the possibility of attenuating blood pulses by means of introducing prosthetic viscoelastic materials able to absorb energy and damp such pulses. Vascular prostheses made of polymeric materials modify the mechanical properties of blood vessels. The effect of these materials on the blood pulse propagation remains to be fully understood. Several materials for medical applications, such as medical polydimethylsiloxane or polytetrafluoroethylene, show viscoelastic behavior, modifying the original vessel stiffness and affecting the propagation of blood pulses. This study focuses on the propagation of pressure waves along a pipe with viscoelastic materials using the Maxwell and the Zener models. An expression of exponential decay has been obtained for the Maxwell material model and also for low viscous coefficient values in the Zener model. For relatively high values of the viscous term in the Zener model, the steepest part of the pulse can be damped quickly, leaving a smooth, slowly decaying wave. These mathematical models are critical to tailor those materials used in cardiovascular implants to the mechanical environment they are confronted with to repair or improve blood vessel function.Electronic supplementary materialThe online version of this article (10.1007/s10237-017-0980-9) contains supplementary material, which is available to authorized users.

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Imaging cardiac morphology in hypertrophic cardiomyopathy

Reichek

2015

Current Opinion in Cardiology

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CMR structural features of HCM, including severity and distribution of hypertrophy and fibrosis, can augment clinical evaluation of HCM. New CMR phenotypes, associated papillary muscle, mitral leaflet and myocardial noncompaction abnormalities, role of left atrial enlargement, findings in genotype positive phenotype negative HCM, and emerging methods for the detection of myocardial fiber disarray and altered myocardial stiffness may shed light in coming years.

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A new method for quantification of aortic stiffness in vivo using magnetic resonance elastography (MRE): a translational study from sequence design to implementation in patients

Cited by 3 publications

References 0 publications

Advances and Future Direction of Magnetic Resonance Elastography

Advances and Future Direction of Magnetic Resonance Elastography

Arterial pulse attenuation prediction using the decaying rate of a pressure wave in a viscoelastic material model

Imaging cardiac morphology in hypertrophic cardiomyopathy

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