A new instrument for the rapid preparation of tissue slices

A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy

“…The Krumdieck tissue slicing system (Alabama Research & Development 44 ) was used in accordance with the manufacturer's instructions and previously published techniques. 45 A coring device was used to create an 8 mm diameter core of ovarian cancer samples and human liver samples.…”

Irreversible Binding and Adrenocorticolytic Activity of the DDT Metabolite 3-Methylsulfonyl-DDE Examined in Tissue-Slice Culture

“…Introduced in the early 1980s (13), precision-cut tissue-slice culture has attracted interest as a test system with which to examine drug metabolism in vitro (14)(15)(16)(17). Recently the adrenal medulla has been examined with this method (18,19).…”

“…The results show that adrenal tissue-slice culture is a promising ex vivo test system for future studies on adrenal toxicants in human and wild animals. (13).…”

Application of Precision-Cut Rat Liver Slice to Study the Influence of Monocrotaline, <i>Tussilago farfara</i> Alkaloids on the Expression of Cytochrome P450 Enzymes

“…Since precision-cut liver slice was reported in the early 1980s [6], it has became more and more mature and perfect along with the improvement of culture method [1] [7] [8]. Precision-cut liver slice has been successfully used in the study of drug toxicity mechanism and prediction, the discovery of early toxicity markers and drug metabolism and transformation.…”