A new fluorogenic probe for the selective detection of carbon monoxide in aqueous medium based on Pd(0) mediated reaction

Abstract

A coumarin-based fluorogenic probe, PCO-1, senses carbon monoxide (CO) selectively in HEPES buffer at pH 8.0 through the intramolecular cyclization-elimination pathway based on Pd(0) mediated reaction. The probe exhibits a 'turn-on' response of CO over a variety of relevant reactive oxygen, nitrogen and sulfur species.

Development of a colorimetric and NIR fluorescent dual probe for carbon monoxide

“…The major obstacle in this area is the lack of real-time approaches to selectively track CO in biological systems. Some established approaches for CO detection include gas chromatography, chromogenic detection, laser sensor-infrared absorption, electrochemical assays, etc, [5][6][7][8] [15][16][17][18][19][20] including our newly reported probe. 21 However, almost all of these probes display emissions in the visible region, which greatly restricts their applications in biological imaging, due to the strong autofluorescence and limited tissue penetration.…”

A Highly Selective Fluorescence Turn‐On Probe for the Sensing and Bioimaging of Hypochlorite Anion in Aqueous Media

“…To determine the detection limit, following equation was used. DL= 3σ/S, where σ is the standard deviation of seven replicate measurements of the zero level (σ zero ) and S is the slope of the curve . The fluorescent titration profile of LH with ClO − ion demonstrated that the detection limit of ClO − ion is 75.9 nM (Figure ).…”

Small-molecule fluorescent probes for imaging gaseous signaling molecules: current progress and future implications

“…In 2015, Dhara et al reported a coumarin-based uorescent probe 38 for the detection of CO through a Pd(0)-mediated intramolecular cyclization-elimination reaction. 56 The weak uorescence intensity of the probe was obtained by protecting the hydroxyl group of coumarin via allyl-functionalized carbamate. The proposed detection mechanism may involve the following processes.…”