A New Device (Diagnostotube) for the Localization of Upper Gastrointestinal Bleeding

Behind the Discovery of “Nissenbaum's Fixative”

“…I. Snapper and I published “A New Rapid Method For Preparation Of Exfoliated Cells Obtained From Body Fluids,” (Nissenbaum and Snapper 1961). During my years as a Fellow in Gastroenterology, I developed a cine‐photographic system for gastrointestinal endoscopy (Nissenbaum, DiBianco, and Groisser 1963) and patented a device, which was manufactured commercially, for the localization of gastrointestinal bleeding (Nissenbaum et al 1965). In 1963, I entered private practice in Internal Medicine and Gastroenterology and was ap pointed Assistant Clinical Professor of Medicine at the University of Medicine and Dentistry of New Jersey.…”

Locating the Source of Gastrointestinal Bleeding

“…The Diagnostotube, * a similar device introduced by Nissenbaum and associates, 8 is marked with lead numbers spaced an inch apart within a plastic covering (figure 7). A cotton sheath is placed over the tube, and it is passed into the upper part of the jejunum.…”

A new tube for use in the fluorescein string test: localization of oesophageal and gastric bleeding sites with or without the use of radiography.

“…The fluorescein string test, described originally by Traphagen and Karlan (1958), has received wide acceptance as a safe and accurate method for localizing the site of bleeding from the upper gastrointestinal tract Haynes, Pittman, and Christakis, 1960;Glaser and Charles, 1963;Pittman, 1964;Reisberg and Haubric, 1965;Nissenbaum, Attia, DiBianco, and Groisser, 1965). To perform this test, a radiopaque marked tape or tube is passed orally into the upper intestine and a radiograph of the upper abdomen is obtained to ascertain the position of the device.…”