Juvenile polyps are the most common type of polyps encountered in childhood, found approximately, in 1% of the pediatric population [1]. There is a male predominance [1] and the peak age of occurrence ranges between 2-6 years [1]. Painless rectal bleeding is the most common symptom, found in 90% of cases [1]. With the advent of the colonoscopy, it has been noticed that >50% of the children have >1 polyp and about 60% of the polyps are located proximal to the rectosigmoid [2]. Because juvenile polyps are usually pedunculated, colonoscopic removal is a common and safe practice [2]. Postpolypectomy bleeding is the most common complication of endoscopic polypectomy [3]. Several studies in adults have shown that the size of the polyp is a risk factor for postpolypectomy bleeding [4]. To minimize the risk of postpolypectomy bleeding, several new techniques have been proposed. These include application of detachable snares or endoclips, injections of adrenaline solutions, and several thermal modalities. We report 4 cases of children with large pedunculated colonic polyps, removed endoscopically, having received an adrenaline injection which was administered locally and the application of a detachable snare, to minimize the risk of postpolypectomy bleeding. Then polypectomy was performed using a standard snare