A neural network model of Borderline Personality Disorder

Berdahl, Carl

doi:10.1016/j.neunet.2009.10.007

Cited by 18 publications

(12 citation statements)

References 97 publications

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“…Previous findings of prefrontal dysfunction in patients with BPD 8,9,[53][54][55] suggest that missing inhibitory control by prefrontal areas over the amygdala are a possible mechanism of exaggerated and/or prolonged amygdala response to emotional stimuli in patients with BPD. 56 Our findings support this assumption.…”

Section: Discussionsupporting

confidence: 81%

Emotional modulation of motor response inhibition in women with borderline personality disorder: an fMRI study

Jacob

Zvonik²,

Kamphausen³

et al. 2013

J Psychiatry Neurosci

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Section: Discussionsupporting

confidence: 81%

Emotional modulation of motor response inhibition in women with borderline personality disorder: an fMRI study

Jacob

Zvonik²,

Kamphausen³

et al. 2013

J Psychiatry Neurosci

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“…Such material on brains has parallels with some research exploring BPD – also a psychopathology disproportionately applied to women (see Shaw & Proctor, ); women diagnosed with BPD are pathologized as being faulty, for instance being declared manipulative of others (Watts, ). Berdahl () explained that “functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) [have been used] to gain some insight into how the BPD brain works” (p. 177) and that “studies do converge on the general impression that the BPD brain has some sort of dysfunction in limbic and prefrontal areas” (p. 177).…”

Section: Psychopathology and Ptsd: Critiques And Connectionsmentioning

confidence: 99%

A person-centred political critique of current discourses in post-traumatic stress disorder and post-traumatic growth

Lee

2017

Psychotherapy and Politics International

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This article seeks to contribute to current person‐centred research exploring post‐traumatic stress disorder (PTSD) and post‐traumatic growth (PTG), by offering a person‐centred political critique of some individualizing/pathologizing ways in which these two discourses seem to be developing. Notions of lower resilience (Regel & Joseph, ), faulty brains (Bell, ), lower intelligence (Bomyea, Risbrough, & Lang, ), faulty femininity (Lilly, Pole, Best, Metzler, & Marmar, ) and personal deficits (Joseph, Murphy, & Regel, ) are identified. Some troubling parallels with the borderline personality disorder (BPD) discourse are drawn. Yet, while the meanings/implications of a BPD diagnosis increasingly attract stringent criticism, current PTSD and PTG research is not being sufficiently challenged from a political perspective. The article argues that person‐centred approaches (PCAs) need to be more recognized as treatments for PTSD – this work is already underway (see Murphy, Archard, Regel, & Joseph, , for instance) – and that, concurrently and then increasingly, practitioners of PCAs must intervene in the PTSD discourse, also challenging themselves to conceptualize what is now termed PTSD as actually just one incongruence amongst many, rather than a psychopathology encountered by some (deficient) people.

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“…Other models can be perceived as attempts to integrate higher‐order neural/psychological functions and lower‐order executive mechanisms (e.g. those residing in the hypothalamus and central gray) . Recently, an almost ‘purely’ neural theory of human aggression was also developed .…”

Section: Early‐life Factors Contributing To Antisocial Behaviour In Hmentioning

confidence: 99%

Effects of Adverse Early‐Life Events on Aggression and Anti‐Social Behaviours in Animals and Humans

Haller

Harold

Sandi

et al. 2014

J Neuroendocrinology

138

102

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We review the impact of early adversities on the development of violence and antisocial behaviour in humans, and present three aetiological animal models of escalated rodent aggression, each disentangling the consequences of one particular adverse early-life factor. A review of the human data, as well as those obtained with the animal models of repeated maternal separation, post-weaning social isolation and peripubertal stress, clearly shows that adverse developmental conditions strongly affect aggressive behaviour displayed in adulthood, the emotional responses to social challenges and the neuronal mechanisms activated by conflict. Although similarities between models are evident, important differences were also noted, demonstrating that the behavioural, emotional and neuronal consequences of early adversities are to a large extent dependent on aetiological factors. These findings support recent theories on human aggression, which suggest that particular developmental trajectories lead to specific forms of aggressive behaviour and brain dysfunctions. However, dissecting the roles of particular aetiological factors in humans is difficult because these occur in various combinations; in addition, the neuroscientific tools employed in humans still lack the depth of analysis of those used in animal research. We suggest that the analytical approach of the rodent models presented here may be successfully used to complement human findings and to develop integrative models of the complex relationship between early adversity, brain development and aggressive behaviour.

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A neural network model of Borderline Personality Disorder

Cited by 18 publications

References 97 publications

Emotional modulation of motor response inhibition in women with borderline personality disorder: an fMRI study

Emotional modulation of motor response inhibition in women with borderline personality disorder: an fMRI study

A person-centred political critique of current discourses in post-traumatic stress disorder and post-traumatic growth

Effects of Adverse Early‐Life Events on Aggression and Anti‐Social Behaviours in Animals and Humans

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