A Natural Outbreak of Synovitis Caused by the Viral Arthritis Agent

No, Olson; Dp, Solomon

doi:10.2307/1588231

Cited by 42 publications

(18 citation statements)

References 8 publications

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“…Mycoplasma synoviae-negative chickens in the USA (Olson & Solomon, 1968). In this report a virus, referred to as virus arthritis agent, was associated with swelling and oedema of hock joint, wing joint and digital flexor tendons.…”

Section: Viral Tenosynovitis/arthritis Was First Reported In 1968 Inmentioning

confidence: 78%

The role of avian reoviruses in turkey tenosynovitis/arthritis

et al. 2014

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Turkey arthritis reovirus (TARV) has been isolated from the gastrocnemius tendons and tibiotarsal joint fluid of lame male turkeys >12 weeks old in the Midwest. Two experiments were conducted to compare the pathogenicity in turkeys of three TARVs (TARV-MN2, TARV-MN4 and TARV-O'Neil), one turkey enteric reovirus (TERV strain MN1) and one chicken arthritis reovirus (CARV strain MN1). Two hundred microlitres of virus were inoculated by the oral, intratracheal, or footpad route into 6-day-old poults placed in isolator units. Poults were necropsied at 1 and 4 weeks post infection in Experiment 1, and at 2 and 4 weeks post infection in Experiment 2. Reovirus was detected by reverse transcription-polymerase chain reaction and virus isolation in tendons of TARVinoculated poults at 1, 2 and 4 weeks post infection. TARV-O'Neil and TARV-MN2 were detected in tendons of sentinal birds at 1 and 4 weeks and 1 week p.i., respectively. In general, TARVs produced lymphocytic tenosynovitis of the gastrocnemius and digital flexor tendon sheaths without inflammation of the tendons proper. In Experiment 1, poults inoculated with TARV-MN2 and TARV-O'Neil had significantly higher gastrocnemius tendon inflammation scores, as determined by histology, than those inoculated with TERV-MN1 or CARV-MN1. In Experiment 2, poults inoculated with TARV-MN2 and TARV-O'Neil had significantly higher gastrocnemius tendon inflammation scores than those inoculated with TARV-MN4 and virus-free medium (negative control group). Koch's postulates was fulfilled when TARV-MN2 and TARV-O'Neil were re-isolated from tendons of poults that had originally been challenged with either of these viruses. Results of these experiments indicate that TARVs have a unique ability to induce gastrocnemius tenosynovitis in turkeys and that administration of TARV-O'Neil through the oral or intratracheal route is a reproducible model to study pathogenesis of TARV infection.

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Section: Viral Tenosynovitis/arthritis Was First Reported In 1968 Inmentioning

confidence: 78%

The role of avian reoviruses in turkey tenosynovitis/arthritis

et al. 2014

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“…Five 'prototype' Japanese strains isolated from the digestive tracts of chickens by Kawamura and Tsubahara (1965) were obtained from Dr. J.B. McFerran. Three strains were obtained from Dr. D. Thornton, EK 2286, isolated in Germany from chickens with anaemia and liver and spleen lesions (Vielitz and Landgraf, 1974), the FaheyCrawley virus from a respiratory disease (Fahey and Crawley, 1954), and WVU 2937, an American strain from tendons of arthritic chickens (Olson and Solomon, 1968). Strain VAA from a chicken with viral arthritis was obtained from Dr. N.O.…”

Section: Virusesmentioning

confidence: 99%

Some observations on the isolation and cultivation of avian reoviruses

1982

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SUMMARYFor the cultivation of avian reoviruses a comparison was made of cell cultures of chick embryo fibroblasts, lungs, liver, kidney and chicken kidney and fertile eggs inoculated via the yolk sac, chorioallantoic membrane or allantoic cavity. Chick embryo liver was found to be the most sensitive cell culture method and the yolk sac the best inoculation route for eggs. Chicken kidney cells were second to embryonic liver cells, but peak titres of cell-bound and cell-free virus occurred later than in chick embryo liver.Using the plaque technique, minimal adsorption times for reovirus in embryonic liver and chicken kidney cells were found to be 30 and 45 min respectively. .Plaques produced by six different strains of reovirus in embryonic liver cells were larger and appeared sooner than in chicken kidney cells.

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“…In Brazil the incidence of arthritis in broilers and layers and reovirus isolation from arthritic fluid was reported by Bottino et al (1975). Since the first report in the United States of a field case of viral arthritis/tenosynovitis by Olson and Solomon (1968), the incidence has been reported in broiler chickens in Maine (Johnson and van der Heide, 1971 ;Johnson, 1972), Texas (Glass et al, 1973), and Connecticut (van der Heide et al, 1974). Virus could be isolated from the leg lesions and no Mycoplasma synoviae infections could be found in these cases.…”

Section: Review Of the Literaturementioning

confidence: 97%

“…NATURAL OCCURRENCE Field observations of clinical viral arthritis/tenosynovitis were first reported by Olson and Solomon (1968) in Mycoplasma sywovrâe-negative broiler chickens in the United States. It was not until Mycoplasma synoviae-negative chickens were produced under commercial conditions that it was recognised that avian reovirus could produce tenosynovitis lesions without the presence of mycoplasmal or bacterial agents.…”

Section: Review Of the Literaturementioning

confidence: 99%

Viral arthritis/tenosynovitis: A review

Heide

1977

Avian Pathology

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A review if presented of viral arthritis/tenosynovitis, one of the clinical manifestations of avian reovirus infection in chickens. Since the detection of a viral etiology of arthritis/tenosynovitis in 1957, the disease has been reported in various parts of the world. Pathological features of the disease include inflammatory lesions in the extensor and flexor tendons and tendon sheaths of the posterior limbs and in the tibiotarsal joints. Hepatitis, myocarditis, hydropericardium, as well as intestinal and respiratory tract involvement are described in association with avian reovirus infection. The epizootiology, horizontal and vertical transmission of reovirus, as well as the role of maternal immunity and its application in breeder vaccination for the control of viral arthritis/tenosynovitis are described.

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A Natural Outbreak of Synovitis Caused by the Viral Arthritis Agent

Cited by 42 publications

References 8 publications

The role of avian reoviruses in turkey tenosynovitis/arthritis

The role of avian reoviruses in turkey tenosynovitis/arthritis

Some observations on the isolation and cultivation of avian reoviruses

Viral arthritis/tenosynovitis: A review

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