A Nationwide Population-Based Study of Corrosive Ingestion in Taiwan: Incidence, Gender Differences, and Mortality

Abstract

Corrosive injury results from the intake of corrosive-acid-based chemicals. However, this phenomenon is limited to a small number of cases and cannot be extrapolated to the epidemiology of corrosive injuries in actual situations. This study focuses on the annual incidence of corrosive injury and its connection to gender, risk factors, and in-hospital mortality. All patients with corrosive injury (ICD-9 947.0–947.3) were identified using a nationwide inpatient sample from 1996 until 2010. Chi-squared tests and multivariate logistic regression were used to examine risk factors of gender differences and in-hospital mortality of corrosive injury. Young adults comprised the majority of patients (71.2%), and mean age was 44.6 ± 20.9 years. Women showed a higher incidence rate of corrosive injuries, age, suicide, psychiatric disorder, and systemic complications compared with men (p < 0.001). The present study demonstrated that age (OR = 10.93; 95% CI 5.37–22.27), systemic complications (OR = 5.43; 95% CI 4.61–6.41), malignant neoplasms (OR = 2.23; 95% CI 1.37–3.62), gastrointestinal complications (OR = 2.02; 95% CI 1.63–2.51), chronic disease (OR = 1.30; 95% CI 1.08–1.56), and suicide (OR = 1.23; 95% CI 1.05–1.44) were strongly associated with in-hospital mortality. Educational programs may be helpful for reducing the incidence of ingestion of corrosive chemicals.

Clinico-epidemiological Characteristics of Corrosive Ingestion: A Cross-sectional Study at a Tertiary Care Hospital of Multan, South-Punjab Pakistan

“…The current study discovered that 80.1% cases of corrosive ingestion belonged to the population of 15-30 years age group. It is in contrast to the previous studies conducted in Taiwan and America [ 15 , 16 ]. In a study by Chen et al, patients older than 40 years of age constitute 55.2% of the total sample size.…”

<p>The Association Between Caustic Ingestion and Psychiatric Comorbidity Based on 396 Adults Within 20 Years</p>

“…The broad-spectrum complications place a heavy burden on healthcare organizations. [1][2][3][4][5][6][7][8][9] The extent of damage depends on the chemical properties, amount, concentration, and physical form of the ingested substances. [1][2][3]5,6,[10][11][12][13][14] Patient age, sex, comorbidities, complications, treatment choices, and socioeconomic status have important roles in survival outcomes and postinjury quality of life.…”

“…[1][2][3]5,6,[10][11][12][13][14] Patient age, sex, comorbidities, complications, treatment choices, and socioeconomic status have important roles in survival outcomes and postinjury quality of life. 1,2,4,6,7,12,13,[15][16][17][18][19][20][21] Preventive measures have been widely advocated. 1,6,10,[22][23][24][25] However, the effectiveness of precautions appears unsatisfactory in adults, among whom suicidal intents and deliberate self-harm accounts for the majority of cases.…”

“…1,6,10,[22][23][24][25] However, the effectiveness of precautions appears unsatisfactory in adults, among whom suicidal intents and deliberate self-harm accounts for the majority of cases. 1,4,5,10,17,25 The associated factors include socioeconomic problems, marital/interpersonal conflicts, low educational status, and negligence in handling caustic substances. 14,16,[23][24][25][26][27][28][29] The high prevalence of psychiatric comorbidities (PCs) has been widely reported among caustic injury victims.…”

“…14,16,[23][24][25][26][27][28][29] The high prevalence of psychiatric comorbidities (PCs) has been widely reported among caustic injury victims. 4,10,11,[16][17][18][19]25,27,28,30,31 Nevertheless, the effect of PCs on the clinical features and prognostic outcomes remains unclear because of limited information and scarce reports on long-term prognoses. To investigate the crucial aspects of caustic GI tract injury, we reviewed 396 cases within 20 years at a north Taiwan medical center.…”