A multiparametric analysis based on DCE-MRI to improve the accuracy of parotid tumor discrimination

Xu, Zhifeng; Zheng, Shaoyan; Aizhen, Pan; Cheng, Xiaofang; Gao, Mingyong

doi:10.1007/s00259-019-04447-9

Cited by 40 publications

(53 citation statements)

References 17 publications

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“…An image histogram represents a map of pixel intensity values, which shows the number of pixels with the same intensity from the entire image. The ADC parameters used in the histogram analysis are mean value, standard deviation, maximum, minimum, kurtosis, smoothness, and ADC percentiles (10,50,90,99). The use of histogram analysis and ADC measurement of ROIs distributed across all DWI sections to cover the entire tumor may provide additional information and can increase DWI accuracy in parotid tumors diagnosis [27,40].…”

Section: Functional Mri Investigationsmentioning

confidence: 99%

“…Following the study of Yabuuchi et al [44], more recent studies on the utility of DCE-MRI in the differential diagnosis of parotid tumors have been published. Their authors used various threshold values for T peak (60-210 seconds) and WRs (10-40%), most of them reporting results that demonstrated the success of investigation in parotid tumors differentiation [15,20,[29][30][31]36,37,[45][46][47][48][49][50][51].…”

Section: Functional Mri Investigationsmentioning

confidence: 99%

“…After analyzing the studies included in the current review, PMA had a type A TIC curve, WT presented a type B TIC (C or D [30,46]), and malignant tumors registered type C TIC curves ( Figure 6) [29,36,37,49,50].…”

Section: Functional Mri Investigationsmentioning

confidence: 99%

“…K trans is in relation to the vascular permeability and K ep is associated with the wash-out phase [24]. Quantitative analysis detects tumor angiogenesis [15,50].…”

Section: Functional Mri Investigationsmentioning

confidence: 99%

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Cross-sectional imaging and cytologic investigations in the preoperative diagnosis of parotid gland tumors – an updated literature review

Stoia

Băciuț

Lenghel

et al. 2020

Bosn J of Basic Med Sci

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An accurate preoperative diagnosis of parotid tumors is essential for selection and planning of the surgical treatment. Various modern cross-sectional imaging and cytologic investigations can support differential diagnosis of parotid tumors. The aim of this study was to achieve a comprehensive and updated review of modern imaging and cytologic investigations used in parotid tumor diagnosis, based on the latest literature data. This literature review could serve as a guide for clinicians in selecting different types of investigations for preoperative differential diagnosis of parotid tumors. Magnetic resonance imaging (MRI) with its dynamic and advanced sequences is the first-line imaging investigation used in differentiating parotid tumors. Computed tomography (CT) and positron emission tomography (PET)-CT provide limited indications in differentiating parotid tumors. Fine needle aspiration biopsy and core needle biopsy can contribute with satisfactory results to cytological diagnosis of parotid tumors. Dynamic MRI with its dynamic contrast-enhanced and diffusion-weighted sequences provides the best accuracy for preoperative differential diagnosis of parotid tumors. CT allows the best evaluation of bone invasion, being useful when MRI cannot be performed, and PET-CT has value in the follow-up of cancer patients. The dual cytological and imaging approach is the safest method for an accurate differential diagnosis of parotid tumors.

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Section: Functional Mri Investigationsmentioning

confidence: 99%

Section: Functional Mri Investigationsmentioning

confidence: 99%

Section: Functional Mri Investigationsmentioning

confidence: 99%

“…K trans is in relation to the vascular permeability and K ep is associated with the wash-out phase [24]. Quantitative analysis detects tumor angiogenesis [15,50].…”

Section: Functional Mri Investigationsmentioning

confidence: 99%

See 2 more Smart Citations

Cross-sectional imaging and cytologic investigations in the preoperative diagnosis of parotid gland tumors – an updated literature review

Stoia

Băciuț

Lenghel

et al. 2020

Bosn J of Basic Med Sci

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“…Perfusion imaging can reflect the essential area of induced brain metabolism [14]. Dynamic contrast enhancement (DCE) is the primary technique for perfusion MRI in the clinic which can be used to estimate several hemodynamic parameters, such as cerebral blood flow (CBF), cerebral blood volume (CBV), and time-to-peak (TTP),which depends on the destruction of blood brain barrier [16]. However, the clinical application of DCE is limited due to its prolonged imaging time and high degree of trauma [17].…”

Section: Introductionmentioning

confidence: 99%

The Study of Cerebral Blood Flow Variations Following Radiation Dose Gradients for Brain Metastasis Patients During Radiotherapy

Hou

Gong

Wang

et al. 2020

Preprint

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Brackground: Changes of cereberal blood flow in different brain regions of patients with brain metastases after radiotherapy are worth exploring. This study aims to investigate the radiation dose range of normal brain tissue and tumor target area by evaluating the cerebral blood flow(CBF) for brain metastases (BMs) patients applying with 3D arterial spin labeling (ASL).Methods: A total of 26 patients harboring 54 BMs treated with radiotherapy (RT) were imaged with magnetic resonance (MR) before and 30-40Gy post RT. The high signal area of BMs on enhanced T1-weighted images (T1WI), normal brain tissue, and peritumoral edema region were defined as regions of interest (ROIs). Changes and correlation of largest cross-sectional area and maximum CBF in BMs before and after RT were analyzed. Maximum CBF change in the three ROIs under different gradients created by thresholding the individual dose maps at 10 Gy steps were assessed.Results: In terms of 54 BMs, a significant decrease of CBF of 29.64% (P<0.05) compared to largest cross-sectional area of 26.46% (P<0.05). The decrease of CBF was more pronounced for 30-40 Gy (33.75%) than for 40-50Gy and >50Gy (24.61% and 27.55%). In normal brain tissue with dose gradients of 30-40Gy, CBF decreased to the maximum, 20.23% (P<0.05),which was similar to BMs. In contrast, the decrement rate of CBF in the peritumoral edema region increased as the dose gradients increased.Conclusions: CBF decreased significantly during the course of RT. According to CBF variations, the dose to the normal brain tissue should be controlled below 30 Gy as much as possible, whereas tumor with high perfusion and peritumoral edema region should be given a higher dose.

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Multiparametric Magnetic Resonance Imaging for the Diagnosis and Differential Diagnosis of Parotid Gland Tumors

Gökçe

2020

Magnetic Resonance Imaging

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The majority of salivary gland tumors occur in the parotid glands. Characterization (ie, benign or malignant, and histological type), location (deep or superficial), and invasion into the neighboring tissues of parotid tumors determine preoperative treatment planning. MRI gives more information than other imaging methods about the internal structure, localization, and relationship with other tissues of parotid tumors. Functional MRI methods (diffusion‐weighted imaging, dynamic contrast‐enhanced MRI, perfusion‐weighted MRI, MR spectroscopy, etc.) have been increasingly used recently to increase the power of radiologists to characterize the tumors. Although they increase the workload of radiologists, the combined use of functional MRI methods improves accuracy in the differentiation of the tumors. There are a wide range of studies in the literature dealing with the combined use of different functional imaging methods in combination with conventional sequences. The aim of the present review is to evaluate conventional and functional/advanced MR methods, as well as multiparametric MRI applications combining them in the diagnosis of parotid gland tumors.Evidence Level: 5Technical Efficacy: Stage 3J. Magn. Reson. Imaging 2020;52:11–32.

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A multiparametric analysis based on DCE-MRI to improve the accuracy of parotid tumor discrimination

Cited by 40 publications

References 17 publications

Cross-sectional imaging and cytologic investigations in the preoperative diagnosis of parotid gland tumors – an updated literature review

Cross-sectional imaging and cytologic investigations in the preoperative diagnosis of parotid gland tumors – an updated literature review

The Study of Cerebral Blood Flow Variations Following Radiation Dose Gradients for Brain Metastasis Patients During Radiotherapy

Multiparametric Magnetic Resonance Imaging for the Diagnosis and Differential Diagnosis of Parotid Gland Tumors

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A multiparametric analysis based on DCE-MRI to improve the accuracy of parotid tumor discrimination

Cited by 40 publications

References 17 publications

Cross-sectional imaging and cytologic investigations in the preoperative diagnosis of parotid gland tumors – an updated literature review

Cross-sectional imaging and cytologic investigations in the preoperative diagnosis of parotid gland tumors – an updated literature review

The Study&nbsp;of&nbsp;Cerebral Blood Flow Variations&nbsp;Following Radiation Dose Gradients for Brain Metastasis&nbsp;Patients During&nbsp;Radiotherapy

Multiparametric Magnetic Resonance Imaging for the Diagnosis and Differential Diagnosis of Parotid Gland Tumors

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The Study of Cerebral Blood Flow Variations Following Radiation Dose Gradients for Brain Metastasis Patients During Radiotherapy