Grecae magnificentiae vera admiratio extat templum Ephesiae Dianae CXX annis factum a tota Asia. In solo id palustri fecere, ne terrae motus sentiret aut hiatus timeret, rursus ne in lubrico atque instabili fondamenta tantae molis locarentur, calcatis ea substravere carbonibus, dein velleribus lanae". With these words, Gaius Plinius Secundus, better known as Pliny the Elder, in his Naturalis Historia (XXXVI, §95), described the Temple of Artemis at Ephesus, one of the largest temples built by Greeks and one of the seven wonders in the ancient world. Recent historic studies allowed pointing out that the foundations were composed by a continuous stone plate separated from a thin layer of marshland by means of a layer of clay mixed with charcoal and ashes [Carpani, 2017]. Nowadays those layers are interpreted as a pioneering base isolation system. Actually, several ancient Greek temples were protected by seismic isolation systems. According to Diogenes Laërtius (3 rd century AD), this technique was first used by Theodoros of Samos, a great architect of the 6 th century BC. He applied also a similar technique to the Temple of Hera at Samos, which had a footing foundation with a thin layer of gravel above a deeper layer of sand. Also the Greek colonies on the Black Sea had foundations made of layers of ash mixed with coal and loess. The Walls of Troy VI (ca. 1300 BC) were founded on a compact "cushion of earth", as defined by Blegen who excavated them, which separated the foundation from the rock [Blegen, Caskey, Rawson, 1953]. Finally, at Paestum, Italy, three Doric temples, among these the Temple of Athena (6 th century BC), have a sand layer between the foundations and the soil. Anti-seismic techniques were also used in Chinese monasteries, temples and bridges, as well as for some buildings in Anatolia. In Peru the Monastery of Santa Catalina, about 1000 km south of Lima, has foundations on a 1 m deep isolating layer of sand, allowing the structure to settle without damage. It supported devastating earthquakes. Also the great walls of Cuzco, probably built with the same technique, supported very strong seismic events. The same concept was also used by Frank Lloyd Wright for the Imperial Hotel in Tokyo, whose foundations were placed on a compact soil layer, about 2 m deep, in turn resting on a layer of muddy silts of about 20 m. The construction was completed in 1921 and, probably thanks to this comfortable cushion, supported the 1923 Tokyo earthquake, which caused the collapse of many buildings.