A multicentric Spanish study on the characteristics and survival of gastric adenocarcinoma under the age of 60

Rodríguez-de-Santiago, Enrique; Hernanz, Nerea; Marcos-Prieto, Héctor Miguel; Jorge-Turrión, Miguel Ángel de; Barreiro-Alonso, Eva; Rodríguez-Escaja, Carlos; Jiménez-Jurado, Andrea; Machado-Volpato, Nadja; Pérez-Valle, Isabel; García-Prada, Maria; Sierra-Morales, María; León, Raquel Ríos; Gómez, Laura Núñez; García-de-Paredes, Ana García; Castaño-García, Andrés; Foruny-Olcina, Jose Ramon; Peñas-García, Beatriz; Vázquez-Sequeiros, Enrique; Albillos, Agustı́n

doi:10.1016/j.gastre.2019.07.001

Cited by 2 publications

(2 citation statements)

References 29 publications

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“…Gastric cancer morbidity is the highest in eastern Asia [ 1 ]. Distant metastases to gastric cancer are common at the time of diagnosis [ 2 ]. Metastatic disease is found at the initial diagnosis of 35% to 40% of gastric cancer patients, and 4% to 14% of these have metastatic disease in the liver, followed by the lung, bone, and brain [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

A Predictive Nomogram for Early Mortality in Stage IV Gastric Cancer

et al. 2020

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Background The study was intended to establish predictive nomogram models for predicting total early mortality (the probability of surviving less than or equal to 3 months) and cancer-specific early mortality in patients with stage IV gastric cancer. This was the first study to establish prognostic survival in patients with stage IV gastric cancer. Material/Methods Patients from the SEER database were identified using inclusion and exclusion criteria. Their clinical characteristics were statistically analyzed. The Kaplan-Meier method and the log-rank test were used to compare the influences of different factors on survival time. Logistic regression models were conducted to explore the correlative factors of early mortality. A nomogram was established based on factors significant in the logistic regression model and an internal validation was performed. Results Of the 11,036 eligible patients included in the study, 4932 (44.7%) patients resulted in total early death (42.6% died of the cancer and 2.1% died of other reasons). Larger tumor size, poor differentiation, and liver metastasis were positively related to cancer-specific early mortality. Surgery was negatively related to total early mortality and cancer-specific early mortality, while cardia was only negatively associated with total early death. Predictive nomogram models for total early mortality and cancer-specific early mortality have been validated internally. The areas under the receiver operating characteristics curve were 73.5%, and 68.0%, respectively, and the decision curve analysis also proved the value of the models. Conclusions The nomogram models proved to be a suitable tool for predicting the early mortality in stage IV gastric cancer.

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Section: Introductionmentioning

confidence: 99%

A Predictive Nomogram for Early Mortality in Stage IV Gastric Cancer

et al. 2020

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“…Las áreas de alta incidencia son Asia Oriental, Europa del Este, América Central y del Sur; la mayoría de los casos se diagnostican en una etapa tardía, lo que significa que la mayoría de los pacientes con diagnóstico de CG muere de la enfermedad (1,2) . Sin embargo, la detección y vigilancia de las personas en riesgo puede disminuir la mortalidad por este cáncer (3)(4)(5) . Por ejemplo en el año 1983, el gobierno japonés emitió una ley que exige establecer un sistema de detección del CG.…”

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¿Por qué es importante detectar la gastritis atrófica y la metaplasia intestinal gástrica? ¿Cuál es la forma adecuada de hacerlo?

Sarem¹,

Corti²

2020

Rev Gastroenterol Peru

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La metaplasia intestinal gástrica y la gastritis atrófica son condiciones precancerosas conocidas (CPCs) del estómago, lo que significa que los pacientes con CPCs están en riesgo de desarrollar cáncer gástrico y, por lo tanto, el diagnóstico y la categorización de riesgo para estos pacientes es un tema relevante. El objetivo de esta revisión es proporcionar una actualización sobre el problema, el diagnóstico y el manejo de las CPCs con énfasis en el papel de la detección endoscópica adecuada.

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A multicentric Spanish study on the characteristics and survival of gastric adenocarcinoma under the age of 60

Cited by 2 publications

References 29 publications

A Predictive Nomogram for Early Mortality in Stage IV Gastric Cancer

A Predictive Nomogram for Early Mortality in Stage IV Gastric Cancer

¿Por qué es importante detectar la gastritis atrófica y la metaplasia intestinal gástrica? ¿Cuál es la forma adecuada de hacerlo?

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