A multicenter, randomized, controlled trial testing the effects of acupuncture on allergic rhinitis

Choi, Sun-Mi; Park, J.‐E.; Li, S.‐S.; Jung, Hee Jung; Zi, Ming-jie; Kim, T.‐H.; Jung, So-Young; Kim, A.; Shin, Mi-Suk; Sul, Jae-Uk; Hong, Zhen; Zhao, Jiping; Lee, Sangmin; He, Liyun; Kang, Kyung‐Won; Baoyan, L.

doi:10.1111/all.12053

Cited by 87 publications

(82 citation statements)

References 36 publications

(44 reference statements)

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“…In a number of studies, the effectiveness of acupuncture in regard to quality of life and the reduction of medication as well as significant improvements of the clinical symptoms has already been shown [1, 8, 12, 30, 31]. Even though our results did not show any significant differences of the single symptoms, a significant improvement of the symptoms was observed in the total sum scores in both the acupuncture and loratadine groups during the course of the treatment.…”

Section: Discussioncontrasting

confidence: 60%

“…With a prevalence of 20 to 30%, allergic rhinitis is one of the most frequent atopic diseases in Western Europe [1–3]. It leads to a decrease of the patients' quality of life [4] and causes great cost for medication and social benefits [5].…”

Section: Introductionmentioning

confidence: 99%

“…Despite the conventional forms of therapy, 64% of patients suffering from persistent allergic rhinitis (PER) desire acupuncture as an alternative form of therapy [11]. Two of the latest multicentre and randomised trials found evidence for a significant improvement of symptoms and the quality of life through acupuncture in patients with allergic rhinitis [1, 12]. …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Effectiveness of Acupuncture Compared to Loratadine in Patients Allergic to House Dust Mites

Hauswald¹,

Dill²,

Boxberger³

et al. 2014

Journal of Allergy

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Background. The aim of this work was to evaluate the clinical effectiveness of acupuncture and its impact on the immune system in comparison to loratadine in the treatment of persistent allergic rhinitis caused by house dust mites. Methods. In this study, 24 patients suffering from persistent allergic rhinitis induced by house dust mites were treated either with acupuncture (n = 15) or with loratadine (n = 9). The evaluation of the data was based on the subjective and the objective rhinoconjunctivitis symptom scores, specific and total IgE, and interleukins (IL-4, IL-10, and IFN-γ) as markers for the activity of Th1 or Th2 cells. Results. The treatments with acupuncture as well as with loratadine were considered effective in the patients' subjective assessment, whereby the effect of the acupuncture tended to be assessed as more persistent after the end of treatment. A change in the specific or the total IgE was not detectable in either group. The interleukin profile showed the tendency of an increasing IL-10 value in the acupuncture group. The results of the study show that the effectiveness of acupuncture is comparable to that of loratadine. Conclusion. Acupuncture is a clinically effective form of therapy in the treatment of patients suffering from persistent allergic rhinitis. The results indicate the probability of an immunomodulatory effect.

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Section: Discussioncontrasting

confidence: 60%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Effectiveness of Acupuncture Compared to Loratadine in Patients Allergic to House Dust Mites

Hauswald¹,

Dill²,

Boxberger³

et al. 2014

Journal of Allergy

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“…Asya'da yapılan yeni çalışmalarda akupunkturun PAR'li hastaların semptom ve yaşam kalitelerinde iyileşme sağladığı bildirilse de, uzun süreli ve daha fazla çalışma gerektiği savunulmaktadır (60). AR tedavisinde akupunktur kullanımı ile ilgili randomize kontrollü çalışmalarda akupunkturun etkisini gösteren yeterli kanıt yoktur (10,24).…”

Section: Akupunkturunclassified

New Developments in the Diagnosis and Therapy of Allergic Rhinitis

Özdemir¹,

Elmas²

2017

Asthma Allergy Immunol

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ÖZAllerjik rinit (AR) tüm yaş gruplarında görülen en sık ve kronik hastalıklardan biridir. Allerjik rinit IgE-aracılı nazal havayolunun allerjik enflamasyounu olup hapşırık, gözde kaşıntı-sulanma, burun mukozasının şişlik ve enflamasyonu ile kendini gösterir. Küresel sağlık problemi ve çocukluktan erişkinliğe kadar birçok kişiyi etkileyen ağır bir hastalıktır. Dünyada çocukluk çağı AR prevalansı %0.8 -45 arasında değişmektedir. Türkiye' de değişik bölgelerde sıklığı %2.9-44 olarak bildirilmektedir. Derlememizin amacı AR teşhis ve tedavisinde güncel tedavi ve teşhis yöntemlerini anlatmaktır. Hastalığın astım üzerine ve hastanın hayatına etkisinden dolayı AR en güvenilir ve etkin tedavi yöntemleriyle tedavi edilmelidir. İkinci kuşak antihistaminikler ve intranazal steroidler tedavinin temel taşlardır. Fakat mevcut ilaçların yeni formülasyonları (rupatadin oral solusyonu, hızlı çözünen ebastin tablet ve intranazal flutikazon propionat ve azelastin hidroklorit kombinasyonu vb.), yeni keşfedilmiş moleküller (siklesonid, bilastin, roflumilast vb.), immünolojik hedefi olan tedaviler (omalizumab gibi) ve klasik olmayan tedaviler (homeopatik yöntemler gibi) AR tedavisinde yeni ufukları temsil etmektedir. Allerjik rinitin doğru teşhis edilmesi tedavi başarısında esastır. Teşhiste ümit verici gelişmeler özgün risk molekülünü tanıyan rekombinant allerjenleri kullanan teşhis yöntemlerinden beklenmektedir. Hastaların duyarlı olduğu kişisel molekülleri tanımlayan pür doğal ve rekombinan allerjenler moleküler ya da belirlenmiş komponentin teşhis yöntemiyle saptanabilir. Böylece, belirlenmiş komponente dayalı teşhis yöntemi provokasyon testine olan ihtiyacı azaltabilir ve allerjen immünoterapisinin özgünlüğünü artırabilir. Yine teşhiste, nazal nitrik oksit (nNO) düzeyini ölçmekte günümüzde değişik yöntemler vardır. Azalmış nNO, kistik fibroz için tipik olmakla beraber, primer silyer diskinezide olduğu kadar düşük değildir. nNO'nun AR gibi üst solunum yolu hastalıklarında klinikte kullanımı yaygınlaşmamıştır. ABSTRACTAllergic rhinitis (AR) is one of the most common chronic diseases in all age groups. It is an IgE-mediated allergic inflammation of the nasal airways and is characterized by sneezing, swelling and inflammation of the nasal mucosa as well as itchy and watery eyes. It is a global health problem and a burdensome disorder affecting many people from childhood to adulthood. The prevalence of childhood AR shows wide variation throughout the world, ranging from 0.8 to 45%. The prevalence rates for different regions of Turkey ranges from 2.9 to 44%. The aim of the present review is to provide an update on AR treatment and diagnosis. Because of its burden on patient's lives and its impact on asthma, AR should be taken care of properly with effective and safe treatments. Second-generation antihistamines and intranasal steroids represent the milestone of AR therapy. New formulations of available drugs (rupatadine oral solution, ebastine fast-dissolving tablets, combination of intranasal fluticasone propionate and azelastine hydr...

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“…Nonetheless, two recent welldesigned studies published in peer-reviewed journals showed some benefit on symptom control compared to sham acupuncture. 20,21 At present, the guidelines state that there is sufficient evidence to recommend acupuncture in patients who express an interest. The AAO-HNS guidelines, however, make no recommendation on the use of Chinese herbal therapy due to limited knowledge and concern about standardization and safety of these medicines.…”

mentioning

confidence: 99%