A multi-sensor biological monitoring module built up in LTCC-technology

Smetana, Walter; Balluch, Bruno; Stangl, G.; Gaubitzer, Erwin; Edetsberger, Michael; Köhler, Gabriele

doi:10.1016/j.mee.2007.01.155

Cited by 37 publications

(25 citation statements)

References 2 publications

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“…The final antenna size is 13 × 16 × 2 mm using LTCC dielectric substrate (ε r = 6.7, σ = 0.0026 S/m). LTCC has been tested for biocompatibility and it has already been used in different biological applications [36,37]. The antenna geometry, with the main radiator positioned at the periphery, provides a wide internal space for future embedding of electronic integrated circuits.…”

Section: Methods and Simulation Setupmentioning

confidence: 99%

Detuning Study of Implantable Antennas Inside the Human Body

Vidal¹,

Curto²,

López-Villegas³

et al. 2012

PIER

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Abstract-This study quantifies the detuning and impedance mismatch of antennas implanted inside the human body. Maximum frequency shifts caused by variations in the electrical properties of body tissues and different anatomical distributions were derived. The results are relevant to the design of implantable antennas. They indicate the bandwidth enhancement and initial tuning necessary for correct functioning. The study was carried out using electromagnetic modeling based on the finite-difference time-domain method and highresolution anatomical models. Four anatomical computer models of two adults and two children were used. The implanted antennas operated in the Medical Implant Communication Service band. The most important detuning and impedance mismatch was found for subcutaneous locations and in areas where a layer of fat tissue was present. The maximum frequency shift towards higher frequencies was 70 MHz. The frequency shift did not occur symmetrically around 403 MHz, but was shifted towards higher frequencies.

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Section: Methods and Simulation Setupmentioning

confidence: 99%

Detuning Study of Implantable Antennas Inside the Human Body

Vidal¹,

Curto²,

López-Villegas³

et al. 2012

PIER

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“…This technology has shown appropriate electrical and mechanical properties and high reliability and stability, as well as allowing production of 3D-integrated microstructures [36]. LTCC technology has proven versatile for building complex multilevel channel structures, including large-volume cavities suitable for biological applications [38]. LTCC has been tested for biocompatibility and has been used in various biological applications, such as evaluation of human umbilical vein endothelial cells [33], and multi-sensor monitoring [37].…”

Section: Antenna Designmentioning

confidence: 99%

Multilayered Broadband Antenna for Compact Embedded Implantable Medical Devices: Design and Characterization

García-Miquel¹,

Curto²,

Vidal³

et al. 2017

PIER

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Abstract-Design and characterization of a multilayered compact implantable broadband antenna for wireless biotelemetry applications is presented in this paper. The main features of this novel design are miniaturized size, structure that allows integration of electronic circuits of the implantable medical device inside the antenna, and enhanced bandwidth that mitigates possible frequency detuning caused by heterogeneity of biological tissues. Using electromagnetic simulations based on the finite-difference timedomain method, the antenna geometry was optimized to operate in the 401-406 MHz Medical Device Radio communications service band. The proposed design was simulated implanted in a muscle tissue cuboid phantom and implanted in the arm, head, and chest of a high-resolution whole-body anatomical numerical model of an adult human male. The antenna was fabricated using low-temperature co-fired ceramic technology. Measurements validated simulation results for the antenna implanted in muscle tissue cuboid phantom. The proposed compact antenna, with dimensions of 14 mm × 16 mm × 2 mm, presented a −10 dB bandwidth of 103 MHz and 92 MHz for simulations and measurements, respectively. The proposed antenna allows integration of electronic circuit up to 10 mm × 10 mm × 0.5 mm. Specific absorption rate distributions, antenna input power, radiation pattern and the transmission channel between the proposed antenna and a half-wavelength dipole were evaluated.

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“…Die Folien sind mit unterschiedlichen physikalischen Eigenschaften und in verschiedenen Stä rken (50 mm bis 500 mm) verfü gbar, was neue Anwendungsfelder im Bereich der Keramiktechnologie erö ffnet. Speziell im Bereich der Aktuatorik, Sensorik und Mikrofluidik kö nnen Mikrosysteme (micro-electromechanical-system, MEMS) hergestellt werden, die aus komplexen dreidimensionalen Strukturen bestehen (Smetana et al, 2007;Fercher et al, 2008;Goldbach et al, 2006). Anschließend wurde der laminierte Stapel in einem Sinterofen bei 850 C drei Stunden lang gebrannt.…”

Section: Herstellungsprozessunclassified

Kapillarelektrophoresesystem aus Keramik zur Messung von Ionenkonzentrationen

Fercher¹,

Smetana

Vellekoop³

2009

Elektrotech. Inftech.

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In diesem Beitrag wird ein miniaturisierter Sensor zur Bestimmung von Ionenkonzentrationen in Flü ssigkeiten vorgestellt, der gä nzlich in Keramikfolientechnologie, der so genannten Low Temperature Co-fired Ceramic(LTCC)-Technologie, aufgebaut ist. Die Ionen werden zunä chst mit Hilfe des Prinzips der Kapillarelektrophorese (CE) separiert und anschließend mit einer kontaktlosen Leitfä higkeitsmessung detektiert. Die Vorteile von LTCC liegen in einer einfachen Verarbeitung und einer besseren Einkopplung des Messsignals in den Mikrokanal, da LTCC hohe relative Permittivitä tszahlen aufweist. Dies fü hrt in der Folge zu hö heren Detektionssensitivitä ten. Mit dem Sensorprototyp in Keramiktechnologie wurden erste erfolgreiche CE-Separationen von anorganischen Ionen durchgefü hrt.Schlü sselwö rter: kontaktlose Leitfä higkeitsmessung; Kapillarelektrophorese; LTCC On-chip capillary electrophoresis in ceramics technology for the measurement of ion concentrations.In this work we present a miniaturized sensor build up entirely in Low Temperature Co-fired Ceramic (LTCC) technology for the determination of ion concentrations in fluids. Ions are first separated using a principle called capillary electrophoresis (CE) and are then sensed using contactless conductivity measurement. The device presented has the advantage of simple fabrication and good capacitive coupling to the measurement channel due to the high dielectric constants of the LTCC material.We show the first successful measurements with this setup confirming the feasibility of contactless conductivity detection of inorganic ions after CE separation in a LTCC-fabricated microchannel.

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A multi-sensor biological monitoring module built up in LTCC-technology

Cited by 37 publications

References 2 publications

Detuning Study of Implantable Antennas Inside the Human Body

Detuning Study of Implantable Antennas Inside the Human Body

Multilayered Broadband Antenna for Compact Embedded Implantable Medical Devices: Design and Characterization

Kapillarelektrophoresesystem aus Keramik zur Messung von Ionenkonzentrationen

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