A multi-platform approach to image guided radiation therapy (IGRT)

Amies, Christopher; Bani‐Hashemi, A; Celi, J; Grousset, Guillaume; Ghelmansarai, F.; Hristov, Dimitre; Lane, Derek R.; Mitschke, Matthias; Singh, Ajit Pratap; Shukla, H; Stein, Joerg I.; Wofford, Mark

doi:10.1016/j.meddos.2005.12.013

Cited by 24 publications

(12 citation statements)

References 27 publications

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“…There are several commercial implementations of a diagnostic CT scanner placed in the treatment room to enable scanning of the patient in the treatment position. Descriptions of the operational characteristics and clinical applications of CT on rails systems are reported in the literature [71][72][73][74][75][76].…”

Section: Ct On Railsmentioning

confidence: 99%

A review of image-guided radiotherapy

Chen

Sharp

Mori³

2009

Radiol Phys Technol

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Image-guided radiotherapy (IGRT) is in the midst of a strong development and implementation cycle, stimulated by pioneering work performed in Japan. We present a review of the rationale, technology, and methodology of image guidance, as well as an overview of current work in IGRT at the Massachusetts General Hospital. The technology is rapidly evolving, and synergisms between the various acquisition approaches are converging to provide unparalleled information on target and normal tissue location and motion. With these new approaches to patient localization, we expect improved clinical results to be forthcoming.

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Section: Ct On Railsmentioning

confidence: 99%

A review of image-guided radiotherapy

Chen

Sharp

Mori³

2009

Radiol Phys Technol

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“…Although this architecture includes software products and assets designed by IBM, it can logically be extended to fit other vendors' products as well. Our approach is to present a generalpurpose platform for managing clinical submissions of imaging biomarker data, in contrast to the specialized portals proposed by Pivovarov et al 37 and Amies et al 38 At the lowest data layer, summarized clinical submission data in the SDTM format feeds (as exported by SAS) into JANUS from a Clinical Data Management System (CDMS) 39,40 that stores CRFs (Case Report Forms). The associated metadata for the SDTM submission is mapped into the tables in the JANUS repository.…”

Section: Proposed It Architecture For Imaging Biomarkersmentioning

confidence: 99%

IT solutions for imaging biomarkers in biopharmaceutical research and development

Hehenberger¹,

Chatterjee²,

Reddy³

et al. 2007

IBM Syst. J.

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Biomarkers are indicators of normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention. The biopharmaceutical industry is building significant molecular-imaging capabilities and in this context is incorporating biomarker concepts throughout its research. In this paper, we discuss and propose information technology (IT) standards and architectures that support incorporation of imaging biomarkers into the drug discovery and clinical development process. In particular, we cover various uses of emerging imaging technologies in biopharmaceutical research and development, examples of imaging biomarkers in therapeutic areas, IT requirements related to the use of imaging technologies, challenges related to the integration of imaging biomarker data with clinical and genotypic data, and the need to integrate external public data sources. We discuss IT standards and architectures associated with the inclusion of biomarker-related data in the submission of new drug applications, with emphasis on imaging technologies. We suggest extensions to the Study Data Tabulation Model of the Clinical Data Interchange Standards Consortium and the JANUS Data Model of the Food and Drug Administration with data elements based on imaging biomarkers.

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“…In these cases, radiopaque seeds may be implanted near the tumor mass to help the identification of the target. Further image-guidance technologies (ultrasonography, markerless fluoroscopy) have been explored (16,(23)(24)(25)(26)(27)(28)(29).…”

Section: Introductionmentioning

confidence: 99%

Commissioning and Quality Assurance of an Integrated System for Patient Positioning and Setup Verification in Particle Therapy

Pella

Riboldi

Tagaste

et al. 2014

Technol Cancer Res Treat

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In an increasing number of clinical indications, radiotherapy with accelerated particles shows relevant advantages when compared with high energy X-ray irradiation. However, due to the finite range of ions, particle therapy can be severely compromised by setup errors and geometric uncertainties. The purpose of this work is to describe the commissioning and the design of the quality assurance procedures for patient positioning and setup verification systems at the Italian National Center for Oncological Hadrontherapy (CNAO). The accuracy of systems installed in CNAO and devoted to patient positioning and setup verification have been assessed using a laser tracking device. The accuracy in calibration and image based setup verification relying on in room X-ray imaging system was also quantified. Quality assurance tests to check the integration among all patient setup systems were designed, and records of daily QA tests since the start of clinical operation (2011)

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A multi-platform approach to image guided radiation therapy (IGRT)

Cited by 24 publications

References 27 publications

A review of image-guided radiotherapy

A review of image-guided radiotherapy

IT solutions for imaging biomarkers in biopharmaceutical research and development

Commissioning and Quality Assurance of an Integrated System for Patient Positioning and Setup Verification in Particle Therapy

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