“…Seven studies assessed the effectiveness of splints (14, 17, 42, 44–47), 3 assessed the effectiveness of exercises (16, 43, 48), and 2 assessed the effectiveness of a combination of splints and exercises (15, 49). Six studies compared splints of different design (42, 44–47, 49), and 3 studies included a control group that did not use any splint (14, 17, 45). Two of the exercise studies compared exercise versus treatment as usual (43, 48), while the third exercise study compared exercise with a sham hand cream (16).…”