A molecular dynamics investigation on transporting mechanism of glucose through a cyclic peptide nanotube

Over the past few years, nanoparticles have been widely used in therapeutic applications. It is well acknowledged that the shortcomings of conventional treatments have been improved by nanoparticles. The advantages and drawbacks of inorganic nanocarriers such as metal nanoparticles and quantum dots have been extensively studied. Although carbon nanotubes have been touted as a prominent medication delivery method, their physicochemical characteristics viz. low water solubility, limited circulation time, etc restrict their use. In comparison to hard matter tubes like carbon and other inorganic matter, organic nanotubes have better physiological properties such as improved blood stability, longer circulation time, high serum solubility, etc. The current study focuses on recent developments in the use of organic nanotubes for drug delivery and the utilization of their structural features. The soft, organic material that build up these nanotubes has a synergistic effect on biocompatibility and lowers cytotoxicity thus proving suitable for the potential use as drug delivery carrier. The goals of this review are to identify the characteristics that support the creation of new drug delivery systems and to shed light on current advancements that have been reported in the literature. The paper also includes discussion of the difficulties in using these organic nanotubes for applications in drug delivery as well as the potential for future research in this field.

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A molecular dynamics investigation on transporting mechanism of glucose through a cyclic peptide nanotube

Cited by 3 publications

References 66 publications

Evaluation of transport mechanism of ascorbic acid through cyclic peptide-based nanotubes: A molecular dynamics study

Evaluation of transport mechanism of ascorbic acid through cyclic peptide-based nanotubes: A molecular dynamics study

An Investigation into the Usage of Monosaccharides with GLUT1 and GLUT3 as Prognostic Indicators for Cancer

Recent Developments in Organic Nanotubes for Drug Delivery Applications

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